Abstract
The orexins neuropeptides are classified as consisting of two subtypes, orexin-orexin-A and B derived from the same precursor (pre-pro-orexin) and bind to two G protein-coupled receptors: a receiver (OX1R) selective for orexin-A and receptor 2 (OX2R) for orexin A and B. The orexinergic neurons are located exclusively in the dorsal and lateral hypothalamic and area perifornicial. This regi…