Abstract
The purpose of this study is to evaluate the influence of bone marrow aspirate (BMA) and platelet-rich plasma (PRP) combined or not with with autogenous bone (AB) graft on bone healing in surgically created critical-size defects (CSD) in rat calvaria. 96 rats will be divided into 6 groups: C, BMA, BMA/AB, PRP, PRP/AB and AB. A 5 mm diameter CSD will be created in the calvarium of each ani…