CV Lattes
Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's at Bacharelado em Química from Universidade Federal de Viçosa (2004), bachelor's at Licenciatura em Química from Universidade Federal de Viçosa (2004), master's at Agrochemistry from Universidade Federal de Viçosa (2006) and doctorate at Chemistry from Universidade de São Paulo (2011). Has experience in Chemistry, focusing on Organic Synthesis, acting on the following subjects: ring contraction, total synthesis and medicinal chemistry. (Source: Lattes Curriculum)
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The project aims the preparation of homologues of the natural product RK-682, isolated from Streptomyces strain 88-682, which is a potent inhibitor of the protein phosphatase CDC25B. The preparation of five diferent analogues of RK-682 will be carried out in racemic form for the evaluation of their CDC25 inhibitory activities and their cytotoxic activities against a panel of nine human c…
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