CV Lattes
Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas (FCM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Ciências Farmacêuticas from Universidade de São Paulo (1989), master's at Pharmacology from Universidade Estadual de Campinas (1993) and ph.d. at Pharmacology from Universidade de São Paulo (1998). Has experience in Pharmacology, focusing on General Pharmacology, acting on the following subjects: platelets, platelet, nitration, nitric oxide and aggregation. (Source: Lattes Curriculum)
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Evidence indicates that platelets have an important role in sepsis. In fact, sepsis severity is positively correlated to thrombocytopenia and platelet activity. In sepsis high formation of inflammatory mediators such as tumor necrosis factor-alpha (TNF-±) occurs, besides nitric oxide (NO) and reactive oxygen species (ROS) generation, which contribute to tissue injuries that may culminate …
Severe sepsis is important causes of death in intensive care units and it is trigged primary by gram-negative and gram-positive bacteria. Lipopolysaccharide (LPS) is a component of the outer membrane of Gram negative bacteria and has a pivotal role in inducing Gram negative sepsis. LPS may activate many types of cells leading to activation of nuclear factor kB (NF-kB) and increase of spec…
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| 2 / 0 | Completed scholarships in Brazil |
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