CV Lattes
ORCID
Mayana Zatz is Professor of Human and Medical Genetics. Director of the Human Genome Research Center (Hug-cell) and Nacional Program (INCT): aging and genetics: genomics and metagenomics, at the University of São Paulo ( USP). Graduaded in Biology, USP (1968), Ph.D. in Human and Medical Genetics at USP (1974), and post-doc in medical genetics (1975-1977) at University of California, USA. She is Member of the Brazilian Academy of Sciences and Academy of Sciences for the developing world (TWAS). Was founder and president of the Brazilian Muscular Dystrophy Association (ABDIM) from 1981-2013. Her research in human and medical genetics, are focused mainly in stem-cells (as a tool to understand gene functioning and cell therapy) , aging and neuromuscular disorders focusing the following aspects: gene identification, genotype-phenotype correlations , and mechanisms underlying clinical variability. She is also investigating the use of zika virus against brain cancer. She has published 403 peer-reviewed papers , December 2024 ), which were cited ~ 11509 times (average 40 per paper international ; H index = 59 ;Publon); H=79 (Google Scholar, 27434 citations ), Scopus: H=62, 18357 citations . She has been the mentor of undergraduate and graduate students who presented 53 thesis. Was awarded several international prizes such as: L 'Oreal 's / UNESCO for Women in Science-as the best Latin American researcher in 2001 - TWAS for Research in Medical Sciences in 2004, Mexican Prize of Science and Technology in 2008 and Gaetano Conte in 2011. She was columnist of the weekly magazine VEJA having written more than 250 articles for lay people. She is currently columnist of @radiouspsp , where she discusses new scientific advances twice a month. She is the author of two books Gen ÉTICA and O LEGADO DOS GENES From 2010 to 2012 she was part of the board of revisors (BORE) of scientific journal Science. She has been actively Involved in ethical aspects related to genome research, genetic testing and scientific political decisions regarding the approval of the embryonic stem -cells bill in 2005 and 2008. Currently she is also investigating the genetic variability associated to COVID-19 clinical variability, zika virus against brain tumors and genetic variants of resilience in healthy centenarians and in Duchenne muscular dystrophy.(project MS-CNPq/coalizão) (Source: Lattes Curriculum)
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- Factors responsible for healthy aging versus accelerated neuromuscular aging, AP.TEM
- EMU granted in FAPESP process 13/ 08028-1 - Mayana Zatz: BD FACSymphony" Flow Cytometer, AP.EMU
- Multi-user equipment approved in grant 13/08028-1: single cell analysis chromiun, AP.EMU
(Only some records are available in English at this moment)
- Rapid, low-cost and efficient molecular diagnostics and large-scale population testing strategies for COVID-19 management, AP.R
- National production of genetically modified pigs for organ xenotransplantation in humans, AP.PITE
- Aging and genetic disorders: genomics and metagenomics, AP.TEM
(Only some records are available in English at this moment)
- Lipid Profile Analysis as an Indicator of Healthy Longevity and Functional Aging, BP.TT
- Drug toxicity detection by fluorescent reporters in cardiohepatic co-culture system, BP.DD
- Functional and molecular characterization of the brain in Brazilian super-agers: new perspectives in the understanding of healthy neuro aging, BP.DD
(Only some records are available in English at this moment)
- Evaluation of the Infection Profile and COVID-19 Response in Alveolar Cells Differentiated from iPSCs of Centenarian Volunteers, BP.TT
- "Generation of 3D Cardiac Organoids from iPSCs of Brazilian Supercentenarians", BP.TT
- "Cellular Models in the investigation of active aging in Brazilian centenarians", BP.TT
(Only some records are available in English at this moment)
- Spatial Mapping of glial-vascular Interactions in CADASIL and Centenarians: Implications for Cerebrovascular Resilience, BE.EP.PD
- Endogenous Hepatic Gene Network Activation in iPSCs via CRISPRa for Efficient Generation of Induced Hepatocytes, BE.EP.DD
- Generation of edited DMD pigs with modifications in Notch3, BE.EP.DR
- Deciphering the interplay between Zika virus and the human brain at a high resolution in twins discordant for CONGENITAL ZIKA SYNDROME, BE.EP.DD
- Investigation of possible etoposide-induced hepatocyte maturation mechanisms in vitro, BE.EP.DD
- Investigation of NOTCH rare SNV as protective modifiers in Duchenne muscular dystrophy, BE.EP.PD
(Only some records are available in English at this moment)