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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

SONOGRAPHIC CUTOFF VALUES FOR DETECTION OF ABNORMALITIES IN SMALL, MEDIUM AND LARGE JOINTS: A COMPARATIVE STUDY BETWEEN PATIENTS WITH RHEUMATOID ARTHRITIS AND HEALTHY VOLUNTEERS

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Author(s):
Machado, Flavia Soares [1] ; Vilar Furtado, Rita Nely [1] ; Takahashi, Rogerio Diniz [2] ; Pirosi de Buosi, Ana Leticia [1] ; Natour, Jamil [1]
Total Authors: 5
Affiliation:
[1] Univ Fed Sao Paulo, Escola Paulista Med UNIFESP EPM, Div Rheumatol, BR-04023900 Sao Paulo, SP - Brazil
[2] Univ Fed Sao Paulo, Escola Paulista Med UNIFESP EPM, Dept Radiol, BR-04023900 Sao Paulo, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: ULTRASOUND IN MEDICINE AND BIOLOGY; v. 41, n. 4, p. 989-998, APR 2015.
Web of Science Citations: 3
Abstract

To determine ultrasound measurements indicative of abnormalities in small, medium and large joints, we conducted a cross-sectional study comparing 60 patients with rheumatoid arthritis (RA) and 78 healthy volunteers. A MyLab 60 ultrasound machine (Esaote) and a linear multifrequency probe were used. Quantitative measurements of synovial recesses and semiquantitative measurements of synovial hyperplasia, power Doppler and bone erosion (scores = 0-3) were performed. The cutoff values for synovial recesses indicating RA (receiver operating characteristic curve, area under the curve >0.800) were found to be (radiocarpal) 3.78 mm and (ulnocarpal) 3.07 mm. Those measurements with the greatest chance of indicating RA (logistic regression analysis expressed as odds ratios {[}ORs]) were (p < 0.001) measurements of synovial hyperplasia (ulnocarpal, OR = 100, and radiocarpal, OR = 70); synovial power Doppler (radiocarpal, OR = 66); synovial bone erosion (radiocarpal, OR = 324); fifth metatarsophalangeal joint (OR5100); and second metacarpophalangeal joint (OR = 92). We concluded that for both quantitative and semiquantitative ultrasound measurements, radiocarpal abnormalities increase the chance of detecting RA. (C) 2015 World Federation for Ultrasound in Medicine \& Biology. (AU)

FAPESP's process: 09/54559-3 - Articular sonography: findings in normal subjets compared with rheumatoid arthritis pacients
Grantee:Jamil Natour
Support type: Regular Research Grants