Mismatch negativity in children with specific lang... - BV FAPESP
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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Mismatch negativity in children with specific language impairment and auditory processing disorder

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Author(s):
Rocha-Muniz, Caroline Nunes [1] ; Befi-Lopes, Debora Maria [1] ; Schochat, Eliane [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Sch Med, Sao Paulo, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Brazilian Journal of Otorhinolaryngology; v. 81, n. 4, p. 408-415, JUL-AUG 2015.
Web of Science Citations: 6
Abstract

INTRODUCTION: Mismatch negativity, an electrophysiological measure, evaluates the brain's capacity to discriminate sounds, regardless of attentional and behavioral capacity. Thus, this auditory event-related potential is promising in the study of the neurophysiological basis underlying auditory processing.OBJECTIVE: To investigate complex acoustic signals (speech) encoded in the auditory nervous system of children with specific language impairment and compare with children with auditory processing disorders and typical development through the mismatch negativity paradigm.METHODS: It was a prospective study. 75 children (6-12 years) participated in this study: 25 children with specific language impairment, 25 with auditory processing disorders, and 25 with typical development. Mismatch negativity was obtained by subtracting from the waves obtained by the stimuli /ga/ (frequent) and /da/ (rare). Measures of mismatch negativity latency and two amplitude measures were analyzed.RESULTS: It was possible to verify an absence of mismatch negativity in 16% children with specific language impairment and 24% children with auditory processing disorders. In the comparative analysis, auditory processing disorders and specific language impairment showed higher latency values and lower amplitude values compared to typical development.CONCLUSION: These data demonstrate changes in the automatic discrimination of crucial acoustic components of speech sounds in children with specific language impairment and auditory processing disorders. It could indicate problems in physiological processes responsible for ensuring the discrimination of acoustic contrasts in pre-attentional and pre-conscious levels, contributing to poor perception. (AU)

FAPESP's process: 11/23131-8 - ENCODING OF TEMPORAL AND SPECTRAL CHARACTERISTICS OF COMPLEX STIMULI IN THE AUDITORY BRAINSTEM
Grantee:Caroline Nunes Rocha-Muniz
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 09/18417-0 - Acoustic signals processing of different complexities in children with auditory or language perception impairment
Grantee:Caroline Nunes Rocha-Muniz
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)