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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Hippo pathway deregulation: implications in the pathogenesis of haematological malignancies

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Author(s):
Cacemiro, Maira da Costa ; Berzoti-Coelho, Maria Gabriela ; Cominal, Jucara Gastaldi ; Burin, Sandra Mara ; de Castro, Fabiola Attie
Total Authors: 5
Document type: Review article
Source: Journal of Clinical Pathology; v. 70, n. 1, p. 9-14, JAN 2017.
Web of Science Citations: 0
Abstract

The Hippo pathway participates in the regulation of cell proliferation, differentiation and apoptosis. It is composed by a large array of proteins whose deregulation has been associated with pro-oncogenic and antioncogenic processes. The present review focuses on the Hippo pathway signalling network and discusses its dual role in oncogenesis, particularly in haematological malignancies. (AU)

FAPESP's process: 15/25637-7 - Epigenetic modulation of apoptotic machinery in Bcr-Abl positive cells by BmooLAAO-I and MjTX-I toxins
Grantee:Sandra Mara Burin de Menezes
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 15/23555-3 - Regulators microRNAs of Hippo pathway in chronic myeloid leukemia
Grantee:Maria Gabriela Berzoti Coelho
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 14/04234-9 - Expression of molecules of HIPPO/LATS pathway in chronic neoplasms myeloproliferative
Grantee:Maira da Costa Cacemiro
Support type: Scholarships in Brazil - Doctorate