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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The influence of anthropogenic habitat fragmentation on the genetic structure and diversity of the malaria vector Anopheles cruzii (Diptera: Culicidae)

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Author(s):
Multini, Laura Cristina [1] ; da Silva de Souza, Ana Leticia [2] ; Marrelli, Mauro Toledo [1, 2] ; Bruno Wilke, Andre Barretto [1, 3]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Sch Publ Hlth, Dept Epidemiol, Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Sao Paulo Inst Trop Med, Sao Paulo, SP - Brazil
[3] Univ Miami, Miller Sch Med, Dept Publ Hlth Sci, 1120 Northwest 14th St, Miami, FL 33136 - USA
Total Affiliations: 3
Document type: Journal article
Source: SCIENTIFIC REPORTS; v. 10, n. 1 OCT 22 2020.
Web of Science Citations: 6
Abstract

Fragmentation of natural environments as a result of human interference has been associated with a decrease in species richness and increase in abundance of a few species that have adapted to these environments. The Brazilian Atlantic Forest, which has been undergoing an intense process of fragmentation and deforestation caused by human-made changes to the environment, is an important hotspot for malaria transmission. The main vector of simian and human malaria in this biome is the mosquito Anopheles cruzii. Anthropogenic processes reduce the availability of natural resources at the tree canopies, An. cruzii primary habitat. As a consequence, An. cruzii moves to the border of the Atlantic Forest nearing urban areas seeking resources, increasing their contact with humans in the process. We hypothesized that different levels of anthropogenic changes to the environment can be an important factor in driving the genetic structure and diversity in An. cruzii populations. Five different hypotheses using a cross-sectional and a longitudinal design were tested to assess genetic structure in sympatric An. cruzii populations and microevolutionary processes driving these populations. Single nucleotide polymorphisms were used to assess microgeographic genetic structure in An. cruzii populations in a low-endemicity area in the city of Sao Paulo, Brazil. Our results show an overall weak genetic structure among the populations, indicating a high gene flow system. However, our results also pointed to the presence of significant genetic structure between sympatric An. cruzii populations collected at ground and tree-canopy habitats in the urban environment and higher genetic variation in the ground-level population. This indicates that anthropogenic modifications leading to habitat fragmentation and a higher genetic diversity and structure in groundlevel populations could be driving the behavior of An. cruzii, ultimately increasing its contact with humans. Understanding how anthropogenic changes in natural areas affect An. cruzii is essential for the development of more effective mosquito control strategies and, on a broader scale, for malariaelimination efforts in the Brazilian Atlantic Forest. (AU)

FAPESP's process: 14/50444-5 - Biodiversity of mosquitoes (Diptera: Culicidae) in the Parque Estadual da Cantareira, and in the Environmental Protection Area Capivari-Monos, State of São Paulo
Grantee:Mauro Toledo Marrelli
Support type: BIOTA-FAPESP Program - Regular Research Grants
FAPESP's process: 14/10919-4 - Epidemiologic aspects of human and simian malaria in areas of Atlantic Forest in the vicinity of the City of São Paulo: study the Anopheles fauna and natural infection by Plasmodium sp. in Parelheiros and Serra da Cantareira
Grantee:Ana Maria Ribeiro de Castro Duarte
Support type: Regular Research Grants
FAPESP's process: 15/23386-7 - Microevolution studies in Anopheles cruzii (Diptera: Culicidae), using wing geometric morphometric and microsatellite loci.
Grantee:Laura Cristina Multini
Support type: Scholarships in Brazil - Doctorate