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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Technical Note: Three-dimensional QA of simultaneous integrated boost radiotherapy treatments by a dose-volume histogram methodology and its comparison with 3D gamma results

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Acurio, Erick Sebastian Rundo [1] ; Lizar, Jessica Caroline [2] ; Arruda, Gustavo Viani [3] ; Pavoni, Juliana Fernandes [2, 3]
Total Authors: 4
[1] Hosp Metropolitano, Radiotherapy Dept, Av Mariana Jesus, Quito - Ecuador
[2] Univ Sao Paulo, Dept Phys, Fac Philosophy Sci & Letters Ribeirao Preto, Av Bandeirantes 3900, BR-14040900 Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Radiotherapy Dept, Ribeirao Preto Med Sch Hosp & Clin, Av Bandeirantes 3900, BR-14040900 Ribeirao Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Medical Physics; v. 48, n. 6 MAY 2021.
Web of Science Citations: 0

Purpose Intensity-modulated radiotherapy with simultaneous integrated boost (SIB) presents several attractive advantages to be employed in clinical practice. Its secure application demands a rigorous quality assurance (QA) procedure, ideal for three-dimensional (3D) dose distribution measurements. Thus, a gel dosimetry methodology to evaluate the dose delivery of SIB treatments is presented and compared to conventional gamma evaluation. Methods MAGIC-f gel dosimeter with magnetic resonance images for dose reading were used following its standard procedures. Four SIB QA plans created in gel dosimeter phantoms were used. The gel measured and treatment planning system (TPS) calculated doses were compared using 3D gamma analyses (3%/3mm/15% threshold). Two structures were artificially on the TPS dose distribution expected on the phantom by converting the 1.7 and 2.0 Gy isodose levels into structures to represent the treatment. The gel and TPS dose-volume histogram (DVH) were compared based on five dose points: D95%, D90%, D50%, D10%, and D5%. Results Approvals of 93%, 96%, 98%, and 92% were achieved in the 3D gamma analyses for the plans QA 1, 2, 3, and 4. In the DVH analyses, QA plan 1 measured and expected curves showed a good agreement. QA plan 2 showed deviations in the highest doses for both structures with a maximum deviation (Delta(max)) of 8.0%. QA plans 3 and 4 showed the highest dose variation between the gel and TPS in the smaller doses of the DVH (Delta(max) of 7.2% and -8.9%, respectively). For QA plan 4, the curves of the 1.7 Gy structure presented a good agreement, but deviations in the smaller dose region of the DVH occurred for the 2 Gy structure (Delta(max) of 7.7%). Conclusions A methodology for 3D dose evaluation of complex SIB treatments was proposed. It provided an important overview of the dose distributions. Their results significantly complemented the usual gamma analysis results. (AU)

FAPESP's process: 14/03370-6 - Clinical applications and optimization of polymeric gel dosimetry technique
Grantee:Juliana Fernandes Pavoni
Support type: Regular Research Grants