Pelvic floor dysfunctions in women with systemic lupus erythematosus: A cross-sectional study

Author(s)

Bifani, Bianca Escuer ; Sato, Tatiana de Oliveira ; dos Santos, Gabriel Bernardi ; Serrao, Paula Regina Mendes da Silva ; Rocha, Ana Paula Rodrigues ; Carvalho, Cristiano

• Document type: Journal article
• Source: INTERNATIONAL UROGYNECOLOGY JOURNAL; v. N/A, p. 9-pg., 2022-08-01.

Abstract

Introduction and hypothesis As a result of the impairment of the musculoskeletal system, the pelvic floor muscles are likely compromised in women with systemic lupus erythematosus (SLE). We hypothesized that women with SLE would report more symptoms of pelvic floor dysfunction (PFD) and there will be an association between SLE and PFD. Methods An online cross-sectional survey was conducted. Data were collected on demographic and anthropometric characteristics, PFD (urinary incontinence, nocturia, anal incontinence, genital-pelvic pain/penetration disorder and pelvic organ prolapse) and obstetric history using a web-based questionnaire. The groups were compared using the Mann-Whitney test for quantitative variables and the chi-squared test for categorical variables. The association between SLE and PFD was tested using logistic regression analysis. Results A total of 196 women answered the questionnaire (102 with SLE and 94 healthy controls). Women with SLE reported significantly more urinary incontinence, nocturia, anal incontinence, pelvic organ prolapse and genital-pelvic pain/penetration disorder than the healthy controls (p <= 0.05). Women with SLE were 2.8- to 3.0-fold more likely to report genital-pelvic pain/penetration disorder than healthy women. Conclusions The prevalence of PFD was significantly higher in women with SLE compared to healthy women. Thus, PFD seems to be an important problem in women with this disease. An in-depth investigation of these disorders could contribute to the understanding of how SLE impacts pelvic floor function. (AU)

• FAPESP's process: 17/20057-8 - Hip muscles function in trunk and lower limb kinematics during single-leg squat and functional performance in individuals with Isolated Patellofemoral Osteoarthritis
• Grantee: Cristiano Carvalho
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)