Impact of pterygium on central corneal thickness measured by optical coherence tomography in older adults

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Dotto, Pedro Gabriel ; Salomao, Solange Rios ; Fernandes, Arthur Gustavo ; Mitsuhiro, Marcia Regina Kimie Higashi ; Ferraz, Nivea Nunes ; Furtado, Joao Marcello ; Watanabe, Sung Song ; Cypel, Marcela ; Sacai, Paula Yuri ; Cunha, Cristina Coimbra ; Vasconcelos, Galton Carvalho ; Morales, Paulo Henrique ; Cohen, Marcos Jacob ; Cohen, Jacob Moyses ; Campos, Mauro ; Munoz, Sergio ; Belfort Jr, Rubens ; Berezovsky, Adriana

• Document type: Journal article
• Source: EUROPEAN JOURNAL OF OPHTHALMOLOGY; v. N/A, p. 6-pg., 2023-02-01.

Abstract

Purpose To measure the central corneal thickness (CCT) using anterior segment optical coherence tomography (AS-OCT) in older adults with and without pterygium from the Brazilian Amazon Region Eye Survey (BARES). Methods BARES is a population-based epidemiological cross-sectional study conducted in Parintins city. Participants were residents >= 45 years of age identified through a door-to-door interview. Eligible participants were invited for a comprehensive eye exam. Pterygium occurrence and severity were assessed by ophthalmologists through slit-lamp examination considering its location (nasal or/and temporal) and severity (lesion with extension <3 mm, >= 3 mm not reaching the pupillary margin or >= 3 mm reaching the pupillary margin). CCTs were obtained and measurements from the more severely affected eye were included. Images were analyzed offline by masked observers. Results A total of 671 subjects, 533 (79.4%) with pterygium in at least one eye and 138 (20.6%) without pterygium in either eye, were examined. The mean CCT evaluated by multiple linear regression and adjusted for demographic variables and pterygium severity was 521 +/- 34 mu m (median = 521; range = 304-665). Decreased CCT was significantly associated with age and pterygium severity. Individuals aged 65-74 years had CCT 7 mu m thinner than those aged 45-54 years (p = 0.044), individuals aged 75 years and older had CCT 15 mu m thinner than those aged 45-54 years (p = 0.001), and eyes with severe pterygium had CCT 33 mu m thinner than eyes without pterygium (p < 0.001). Conclusions The CCT analysis in this population-based sample shows that a thinner cornea is associated with pterygium severity and older age. (AU)

• FAPESP's process: 13/16397-7 - Eye survey of the city of Parintins, AM: prevalence and causes of near and distance visual impairment and blindness
• Grantee: Solange Rios Salomão
• Support Opportunities: Regular Research Grants