Comparison between FRAIL Scale and Clinical Frailty Scale in predicting hospitalization in hemodialysis patients

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Barbosa, Elisabete Mouzinho Soares ; Pereira, Amanda Gomes ; Mori, Vitoria ; Neves, Renan da Silva ; Vieira, Nayane Maria ; Silva, Maryanne Zilli Canedo ; Seki, Marcos Mitsuo ; Rodrigues, Hellen Christina Neves ; Costa, Nara Aline ; Ponce, Daniela ; Balbi, Andre Luis ; Zornoff, Leonardo Antonio Mamede ; Azevedo, Paula Schmidt ; Polegato, Bertha Furlan ; de Paiva, Sergio Alberto Rupp ; Minicucci, Marcos Ferreira ; Dorna, Mariana de Souza

• Document type: Journal article
• Source: JOURNAL OF NEPHROLOGY; v. N/A, p. 7-pg., 2022-12-22.

Abstract

Background To assess the prevalence of frailty by the Clinical Frailty Scale (CFS) and the 5-item FRAIL scale and their association with hospitalization in hemodialysis (HD) patients.Methods This was a prospective observational study. We included patients of both genders >= 18 years old in HD treatment for at least 3 months. Demographic, clinical, and routine laboratory data were retrieved from the medical charts. Two different frailty assessment tools were used, the CFS and the FRAIL scale. Participants were followed up for 9 months and hospitalizations for all causes were evaluated. A Venn diagram was constructed to show the overlap of possible frailty and pre-frailty. Cox regression was used to identify the association between frailty and hospitalization. The significance level was 5%.Results A total of 137 subjects were included in the analysis. The median age was 61 (52-67) years and 60% were male. The hospitalization rate and mortality in 9 months were 22.6% and 7.29%, respectively. Regarding frailty, the overall prevalence was 13.8% assessed by CFS and 36.5% according to the FRAIL scale. In the Cox regression, frailty by FRAIL scale was associated with a 2.8-fold increase in the risk of hospitalization (OR = 2.880; 95% CI = 1.361-6.096; p = 0.006), but frailty assessed by the CFS was not associated with the need for hospitalization.Conclusion In HD patients, the FRAIL scale proved to be an easy-to-apply tool, identifying a high prevalence of frailty and being a predictor of hospital admission. (AU)

• FAPESP's process: 19/22232-7 - Association between late-night dinner eating and sleep duration with outcomes in patients requiring hemodialysis
• Grantee: Vitória Mori
• Support Opportunities: Scholarships in Brazil - Scientific Initiation