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Spotlight transcriptomics reveals hidden information in trypanosomatids

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Author(s):
Abuchery, Bryan E. ; Black, Jennifer A. ; da Silva, Marcelo S.
Total Authors: 3
Document type: Journal article
Source: Trends in Parasitology; v. 38, n. 1, p. 3-pg., 2021-12-15.
Abstract

Dixenic parasites often encounter environmental extremes during the transition from vector to host. Preadapted transmission stages overcome these challenges to promote parasites' survival and ensure life cycle progression. Recently, Vigneron et al. and Briggs et al. used single-cell transcriptomics to investigate developmental stage specific gene expression patterns during parasite differentiation. (AU)

FAPESP's process: 20/01883-7 - Does signalling during DNA replication stress drive genome diversity in Leishmania?
Grantee:Jennifer Ann Black
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 20/16480-5 - Generation of T. cruzi (CL Brener) strains knockout for IP6K and evaluation of homologous recombination (HR) repair capacity
Grantee:Bryan Etindi Abuchery
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 20/10277-3 - Investigation of the role of inositol pyrophosphates (PP-IPs) in DNA repair pathways and telomere dynamics using trypanosomatids as a model
Grantee:Marcelo Santos da Silva
Support Opportunities: Scholarships in Brazil - Young Researchers
FAPESP's process: 19/10753-2 - Investigation on the role of inositol pyrophosphates (PP-IPs) in DNA repair pathways and telomere dynamics using trypanosomatids as a model
Grantee:Marcelo Santos da Silva
Support Opportunities: Research Grants - Young Investigators Grants