Photobiomodulation increases uprighting tooth movement and modulates IL-1β expression during orthodontically bone remodeling

Author(s):Show less -

Murakami-Malaquias-Silva, Felipe ; Rosa, Ellen Perim ; Malavazzi, Taina Caroline Santos ; Silva, Tamiris ; Sarmento, Dmitry Jose de Santana ; Garcez, Aguinaldo Silva ; Fernandes, Marcella Ueda R. ; Tortamano, Andre ; Ramalho, Karen Muller ; Motta, Lara Jansiski ; Fernandes, Kristianne Porta Santos ; Bussadori, Sandra Kalil ; Mesquita-Ferrari, Raquel Agnelli ; Horliana, Anna Carolina Ratto Tempestini

• Document type: Journal article
• Source: Journal of Biophotonics; v. 16, n. 9, p. 12-pg., 2023-06-21.

Abstract

This study investigated the effects of photobiomodulation (PBM) in acceleration of orthodontic movement of inferior molar uprighting movement. Thirty-four individuals, with indication of molar uprighting movement for oral rehabilitation, were randomly divided in two groups: verticalization + PBM (808 nm, 100 mW, 1 J per point, 10 points and 25 J/cm(2)) or verticalization + PBM simulation. Elastomeric chain ligatures were changed every 30 days for 3 months. FBM was performed immediately, 24 h, 72 h, 1 and 2 months after activation. The primary outcome was the amount of uprighting movement. Secondary outcomes were pain, amount of medication, OHIP-14 questionnaire, and cytokine IL-1 beta. PBM group increase uprighting movement when compared to control after 3 months and modulate IL-1 beta expression. For pain control, the amount of medication and OHIP-14 no difference were found. This study suggests that PBM accelerates tooth movement during molar uprighting, due to modulation of IL-1 beta during bone remodeling. (AU)

• FAPESP's process: 15/20535-1 - Evaluation of periodontal treatment in bronchiectasic patients
• Grantee: Anna Carolina Ratto Tempestini Horliana
• Support Opportunities: Regular Research Grants