| Full text | |
| Author(s): |
Quiroga, Cassio de Lima
;
Schimit, Pedro Henrique Triguis
Total Authors: 2
|
| Document type: | Journal article |
| Source: | COMPUTATIONAL & APPLIED MATHEMATICS; v. 42, n. 6, p. 24-pg., 2023-09-01. |
| Abstract | |
Multi-patch and multi-city models have been proposed to investigate the dynamics of disease propagation in discrete regions characterized by varying connectivity and movement rates. This paper aims to comprehensively explore the impact of network topology and travel rates on disease spread within a population represented by random networks of interconnected cities. This approach enables a more comprehensive analysis of disease outbreaks across spatial domains compared to conventional multi-patch models, which typically consider a limited number of homogeneous links among subpopulations within distinct spatial units (i.e., patches). In this study, cities are represented using a probabilistic cellular automaton model that incorporates local interactions among individuals, while the network's edges represent the travel rates between pairs of cities (i.e., nodes). Two types of complex networks are considered, namely small-world and Barabasi-Albert networks. By employing a flexible numerical model, this study surpasses previous models in its capacity to accommodate a larger number of patches or cities. The primary findings of this research reveal that reducing the travel rates within the network can potentially "flatten the curve" of infected cases; however, it does not impact the population's basic reproduction number. To effectively reduce the reproduction number, localized interventions targeting disease transmissibility are required. Additionally, concentrating control efforts on "central" cities within the network may prove crucial in impeding the rapid propagation of the disease. In summary, this study employs a rigorous framework to investigate the influence of network topology and travel rates on disease spreading within a population represented by random networks of interconnected cities. The findings contribute to a comprehensive understanding of disease dynamics in complex spatial settings and inform targeted intervention strategies for controlling and mitigating infectious disease outbreaks. (AU) | |
| FAPESP's process: | 17/12671-8 - Laboratory of populational dynamics |
| Grantee: | Pedro Henrique Triguis Schimit |
| Support Opportunities: | Regular Research Grants |