Influence of the Soil Composition on the Determination of 2,4-D and Fipronil in Environmental Samples by SLE-LC-MS/MS

Author(s)

Goulart, Bianca V. ; Vizioli, Beatriz C. ; Espindola, Evaldo Luiz G. ; Montagner, Cassiana Carolina

• Document type: Journal article
• Source: Journal of the Brazilian Chemical Society; v. N/A, p. 9-pg., 2023-08-01.

Abstract

The main objective of this work was to develop and validate an analytical method using solid-liquid extraction and liquid chromatography coupled with mass spectrometry in tandem (LC-MS/MS) for the simultaneous determination of the herbicide 2-(2,4-dichlorophenoxy)acetic acid (2,4-D) and the insecticide fipronil and its degradation products, fipronil sulfone and fipronil sulfide in different types of soil from Brazil (Oxisol and Entisol). Solid-liquid extraction was performed in two cycles using 20 mL of dichloromethane per cycle and sonication. The extraction efficiency of 2,4-D was more influenced by soil composition than the other compounds. The limits of quantification of the method were between 0.015 and 0.75 mg kg-1 and recovery values from 61 to 118%, with a maximum relative standard deviation (RSD) value of 4%. The method was further applied to over 500 real soil and sediment samples. 2,4-D and fipronil concentrations varied from 0.03 to 1145 & mu;g kg-1 and 1.1 to 282 & mu;g kg-1, respectively. (AU)

• FAPESP's process: 15/18790-3 - Environmental effects of the pasture-sugarcane conversion and pasture intensification
• Grantee: Luiz Antonio Martinelli
• Support Opportunities: Research Program on Global Climate Change - Thematic Grants