The Effect of Transcutaneous Electrical Nerve Stimulation in Peripheral and Central Hemodynamic Parameters on Resistant Hypertension: A Case Report

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Giollo-Junior, Luiz Tadeu ; Cosenso-Martin, Luciana Neves ; Lopes, Valquiria da Silva ; Landim, Manoel Paz ; Fernandes, Leticia Aparecida Barufi ; de Oliveira, Kleber Aparecido ; Spaziani, Amanda Oliva ; Santos, Aleandra Polegati ; Silva, Marco Antonio ; Yugar-Toledo, Juan Carlos ; Vilela-Martin, Jose Fernando

• Document type: Journal article
• Source: VASCULAR HEALTH AND RISK MANAGEMENT; v. 19, p. 7-pg., 2023-01-01.

Abstract

Resistant hypertension (RH) is characterized by being difficult to control, even with the use of various antihypertensive drugs and is associated with target organ lesions and other comorbidities. Thus, new treatment alternatives such as transcutaneous electrical nerve stimulation (TENS) can offer benefits to resistant hypertensive patients by reducing blood pressure (BP) in a noninvasive way and without the need for the association of more antihypertensive drugs. In this case, a patient with RH was submitted to three weekly applications of TENS on the stellate ganglion lasting 40 min each for 1 month. Peripheral and central hemodynamic assessments were performed by 24-h ambulatory BP monitoring (ABPM) before and after TENS applications. After completion of the TENS applications, significant reductions in office systolic (SBP) and diastolic BP (DBP) were observed. There was also a decrease in peripheral SBP and DBP in the 24-h ABPM and sleep and SBP during wakefulness. Additionally, central parameters including central SBP and pulse wave velocity presented a significant reduction in the 24-h ABPM, during the wakefulness and sleep. TENS is able to attenuate the sympathetic hyperactivity present in RH cases and decrease the peripheral and central hemodynamic parameters of a resistant hypertensive patient. (AU)

• FAPESP's process: 16/08203-6 - Arterial stiffness, Genetic Analysis, Cytokines concentration Inflammatory, microparticles and transfer of lipids in Patients with Ischemic Stroke for Hypertensive Emergency
• Grantee: José Fernando Vilela Martin
• Support Opportunities: Regular Research Grants