Ovaries of guppies (Poecilia reticulata) investigated in pre-embryonic, embryonic and post-embryonic stages after exposure to maghemite nanoparticles (y-Fe2O3) associated with Roundup (R) and glyphosate, followed by recovery period evaluation

Author(s)

da Silva, Victoria Costa ; de Lima-Faria, Joao Marcos ; Guimaraes, Lucas Nunes ; Costa, Matheus Santos ; de Lima, Phamella Neres ; Simoes, Karina ; Oliveira de Jesus, Lazaro Wender ; Teixeira de Saboia-Morais, Simone Maria

• Document type: Journal article
• Source: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; v. 100, p. 12-pg., 2023-05-17.

Abstract

Iron oxide nanoparticles (IONP) are promising alternatives to environmental remediation, so this study in-vestigates IONP single and associated to contaminants, in this case, glyphosate (GLY) and Roundup (R) (GBH) in Poecilia reticulata (guppy). The guppies have internal development, therefore this study analyzed female gonads to establish the developmental stages of P. reticulata and evaluate effects of exposure (7, 14 and 21 days) and post-exposure (same period) to the treatments with Iron ions 0.3 mg Fe/L (IFe); IONP 0.3 mg Fe/L; IONP 0.3 mgFe/L + GBH 0,65 mgGLY/L (IONP+GBH1); IONP 0.3 mgFe/L + GBH 1.30 mgGLY/L (IONP+GBH2); and IONP 0.3 mgFe/L + GLY 0.65 mg/L (IONP+GLY). The development was organized in immature, development, and gestation phases. The damage in all treatments after 21 days of exposure was evident in reaction patterns regressive inflammatory, and circulatory including total histopathologic index of liver, nevertheless there was a damage recovery trend during post-exposure period. (AU)

• FAPESP's process: 19/24180-4 - Multiple cellular and tissue biomarkers in guppy (Poecilia reticulata) after long-term exposure to glyphosate, LR microscystin and cylinderspermopsin associated to metal nanoparticles (NANOMBI)
• Grantee: Marisa Narciso Fernandes
• Support Opportunities: Regular Research Grants