Determination of Three-Dimensional Left Ventricle Motion to Analyze Ventricular Dyssyncrony in SPECT Images

Author(s)

Rebelo, Marina de Sa ; Hummelgaard Aarre, Ann Kirstine ; Clemmesen, Karen-Louise ; Soares Brandao, Simone Cristina ; Giorgi, Maria Clementina ; Meneghetti, Jose Claudio ; Gutierrez, Marco Antonio

• Document type: Journal article
• Source: EURASIP JOURNAL ON ADVANCES IN SIGNAL PROCESSING; v. N/A, p. 9-pg., 2010-01-01.

Abstract

A method to compute three-dimension (3D) left ventricle (LV) motion and its color coded visualization scheme for the qualitative analysis in SPECT images is proposed. It is used to investigate some aspects of Cardiac Resynchronization Therapy (CRT). The method was applied to 3D gated-SPECT images sets from normal subjects and patients with severe Idiopathic Heart Failure, before and after CRT. Color coded visualization maps representing the LV regional motion showed significant difference between patients and normal subjects. Moreover, they indicated a difference between the two groups. Numerical results of regional mean values representing the intensity and direction of movement in radial direction are presented. A difference of one order of magnitude in the intensity of the movement on patients in relation to the normal subjects was observed. Quantitative and qualitative parameters gave good indications of potential application of the technique to diagnosis and follow up of patients submitted to CRT. (AU)

• FAPESP's process: 06/06612-4 - Quantification and analysis of dynamic structures in PET and SPECT cardiac images
• Grantee: Marina de Fátima de Sá Rebelo
• Support Opportunities: Regular Research Grants