DNA Nanosensor Surface Grafting and Salt Dependence

Author(s)

Carvalho, B. G. ; Fagundes, J. ; Martin, A. A. ; Raniero, L. ; Favero, P. P. ; Cartwright, AN ; Nicolau, DV

• Document type: Journal article
• Source: NANOSCALE IMAGING, SENSING, AND ACTUATION FOR BIOMEDICAL APPLICATIONS X; v. 8594, p. 7-pg., 2013-01-01.

Abstract

In this paper we investigated the Paracoccidoides brasiliensis fungus nanosensor by simulations of simple strand DNA grafting on gold nanoparticle. In order to improve the knowledge of nanoparticle environment, the addiction of salt solution was studied at the models proposed by us. Nanoparticle and DNA are represented by economic models validated by us in this paper. In addition, the DNA grafting and salt influences are evaluated by adsorption and bond energies calculations. This theoretical evaluation gives support to experimental diagnostics techniques of diseases. (AU)

• FAPESP's process: 11/13250-0 - Minimum model of metallic nanoparticle surface and cluster for DNA nanosensors optimization
• Grantee: Priscila Pereira Fávero
• Support Opportunities: Regular Research Grants