Effect of percutaneous transthoracic lung biopsy on oxidative metabolism in sheep

Advanced search

Search - Use quotation marks to get a more specific result

Index

Field of knowledge

Start date

Betweenand

Full text
Author(s):	Silva, Andreza A. ; Ferreira, Danilo O. L. ; Santarosa, Bianca P. ; Dias, Adriano ; Damasceno, Debora C. ; Goncalves, Roberto C. Total Authors: 6
Document type:	Journal article
Source:	JOURNAL OF THE SOUTH AFRICAN VETERINARY ASSOCIATION; v. 83, n. 1, p. 5-pg., 2012-01-01.
Abstract
This study aimed to assess the effect of percutaneous transthoracic lung biopsy on the oxidative metabolism of sheep by measuring the oxidative stress markers of superoxide dismutase (SOD), total glutathione (GSH-t), peroxidase (GSH-Px) and thiobarbituric acid reactive substances (TBARS) in the red cells of these animals. Blood samples were collected from 20 clinically healthy sheep prior to, and 30 min after, percutaneous transthoracic lung biopsy. After biopsy, there was a significant decrease (p < 0.05) in SOD and GSH-Px activity, with no significant change (p >= 0.05) in GSH-t and TBARS concentrations. These results showed that percutaneous transthoracic lung biopsy did not significantly affect the oxidative metabolism of sheep 30 min after the procedure, which may be used widely in this species without causing serious tissue damage. (AU)