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The use of citalopram for the treatment of cataplexy

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Fonseca, Hassana de Almeida ; Lopes, Danielle Antunes ; Pereira, Danielle ; Sguillar, Danilo Anunciatto ; Lopes, Eduardo ; Costa da Silva Behrens, Nilce Sanny ; de Araujo Lima, Tais Figueiredo ; Pradella-Hallinan, Marcia ; Castro, Juliana ; Tufik, Sergio ; Santos Coelho, Fernando Morgadinho
Total Authors: 11
Document type: Journal article
Source: SLEEP SCIENCE; v. 7, n. 1, p. 3-pg., 2014-03-01.
Abstract

This is a series of cases describing the use of citalopram for the treatment of cataplexy in patients with narcolepsy. Cataplexy is the most specific symptom of narcolepsy, being characterized by a sudden and temporary loss of muscle tonus, triggered by episodes of emotion during vigil. Some antidepressants, besides gamma-hydroxybutyrate, are used for the control of cataplexy. As gamma-hydroxybutyrate is not available in Brazil, local treatment is usually done by the use of antidepressants. Citalopram is a selective inhibitor of serotonin reuptake, with reasonable price and with fewer side effects when compared with other drugs of the same type. In this study, we report a series of cases with patients with narcolepsy and cataplexy, treated with citalopram for the control of cataplexy. (C) 2014 Brazilian Association of Sleep. Production and Hosting by Elsevier B.V. (AU)

FAPESP's process: 98/14303-3 - Center for Sleep Studies
Grantee:Sergio Tufik
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC