| Full text | |
| Author(s): |
Aguiar, Juliana Martins
;
Silva, Sheila Oliveira
;
dos Santos, Valdir Azevedo
;
Taniwaki, Sueli Akemi
;
Ferreira de Sousa Oliveira, Tricia Maria
;
Ferreira, Helena Lage
;
Keid, Lara Borges
;
Gregori, Fabio
;
Soares, Rodrigo Martins
Total Authors: 9
|
| Document type: | Journal article |
| Source: | REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA; v. 25, n. 2, p. 9-pg., 2016-04-01. |
| Abstract | |
Giardia duodenalis is divided into eight assemblages (named A to H). Isolates of assemblage A are divided into four sub-assemblages (AI, AII, AIII and AIV). While isolates of sub-assemblage AII are almost exclusively detected in human hosts, isolates of assemblage B are encountered in a multitude of animal hosts and humans. Here, we isolated single cysts of G. duodenalis from a human stool sample and found that one of them had overlaps of assemblage AII and B alleles and an unexpectedly high number of variants of the beta-giardin (Bg) and GLORF-C4 (OrfC4) alleles. In addition, one of the Bg alleles of that cyst had a fragment of sub-assemblage AII interspersed with fragments of assemblage B, thus indicating that this allele may be a recombinant between sequences A and B. Our results are unprecedented and put a check on the statement that different assemblages of G. duodenalis represent species with different host specificities. (AU) | |
| FAPESP's process: | 11/13472-2 - Genotyping of Giardia duodenalis: detection of mixed infections and genetic recombination in samples of human origin |
| Grantee: | Juliana Martins Aguiar |
| Support Opportunities: | Scholarships in Brazil - Doctorate |