| Full text | |
| Author(s): |
Pereira, Fabio R.
;
Santos, Mario F. C.
;
Williams, David E.
;
Andersen, Raymond J.
;
Padula, Vinicius
;
Ferreira, Antonio G.
;
Berlinck, Roberto G. S.
Total Authors: 7
|
| Document type: | Journal article |
| Source: | Journal of the Brazilian Chemical Society; v. 25, n. 4, p. 7-pg., 2014-04-01. |
| Abstract | |
In the present investigation, two specimens of the nudipleuran mollusc Pleurobranchus areolatus have shown to accumulate oxidized rodriguesin A derivatives. Rodriguesic acid presents a carboxylic acid replacing the terminal methyl group of the alkyl chain of rodriguesin A. A hydroxamate group was also present on the diketopiperazine moiety of a rodriguesic acid derivative. The structures of both rodriguesic acid and of rodriguesic acid hydroxamate have been established by analysis of spectroscopic data, including their absolute configuration. Two methyl esters of the rodriguesic acids have been isolated as major compounds, but were considered to be isolation artifacts. (AU) | |
| FAPESP's process: | 10/50190-2 - Investigation of metabolic and biotechnological potential of marine organisms in bioremediation processes and for the production of substances with anti-viral, anti-inflammatory and anti-Leishmania activities (Marine Biodiversity) |
| Grantee: | Roberto Gomes de Souza Berlinck |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |