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Characterization of Radiochromic Hydrogel Dosimeter-Ferrous Xylenol Orange Enhanced to Have a Higher Melting Point

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Author(s):
da Silveira, Matheus Antonio ; Pavoni, Juliana Fernandes ; Jordan, Kevin ; Baffa, Oswaldo
Total Authors: 4
Document type: Journal article
Source: Brazilian Journal of Physics; v. 54, n. 5, p. 8-pg., 2024-10-01.
Abstract

Ferrous xylenol orange (FXO) radiochromic gelatin gel dosimeter has the potential to provide tridimensional dosimetry for the assessment of new technologies of treatment in radiotherapy. However, one problem with the present formulations of these gels is the low melting point of the gelatin matrix. To solve this problem, formaldehyde was added to this gel dosimeter to promote crosslinking in the gelatin matrix, thus increasing the melting point. Five different formulations of FXO gel were tested, the best melting point temperature found was 62 degrees C or higher, and the 0.210 mm2/hr of diffusion rate was obtained on the 8% gelatin with 3% formaldehyde, 75% lower than original formulation. To provide clinical uses of these dosimeters, this work deals with the dosimetric characterization of modified FXO. No energy dependence was found when irradiated with 6 MV and 15 MV beams; also, no dose rate dependence was found varying low to high dose rate, 100 to 1400 cGy/min. These characteristics allow this dosimeter to useful for clinical context. (AU)

FAPESP's process: 13/07699-0 - Research, Innovation and Dissemination Center for Neuromathematics - NeuroMat
Grantee:Oswaldo Baffa Filho
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 14/03370-6 - Clinical applications and optimization of polymeric gel dosimetry technique
Grantee:Juliana Fernandes Pavoni
Support Opportunities: Regular Research Grants