Desiccation strategies of Cronobacter sakazakii to survive in low moisture foods and environment

Author(s)

Lang, Emilie ; Rhee, Min Suk ; Goncalves, Maria Paula M. B. B. ; Sant'Ana, Anderson S.

• Document type: Journal article
• Source: TRENDS IN FOOD SCIENCE & TECHNOLOGY; v. 143, p. 17-pg., 2023-12-11.

Abstract

Background: Cronobacter sakazakii is one of the pathogens of significant concern in powdered infant formula (PIF), with a death rate of up to 80% infection. However, PIF is characterized by its low water content, which makes it a harmful environment for vegetative bacteria. C. sakazakii can survive in this environment, which complicates the challenge of food safety.Scope and approach: This review discusses the complexity of the desiccation as an environmental perturbation, which can engender different armful change in the environment and the cell. This conduct exposes different mechanisms that permit C. sakazakii to survive this drastic stress, by counterbalancing the effect of desiccation, but also by repairing the eventual damages. The link between desiccation and other environmental stresses commonly food in PIF industries were presented.Key findings and conclusions: The various strategies of C. sakazakii to survive desiccation have a key role in persistence, and among them, common pathways with other Enterobacteriaceae, like the accumulation of osmoprotectant or the production of chaperone proteins that prevent oxidative damages. Nevertheless, other resistance mechanisms seem specific to C. sakazakii as its specific membrane management and still must be better described. Understanding C. sakazakii unique response to desiccation can lead to new opportunities to ensure powdered infants' food safety and properly control this microorganism in the processing environment. (AU)

• FAPESP's process: 22/14938-0 - Salmonella enterica and Cronobacter sakazakii: both pathogens of powdered infant formula: an omic compartive study to understand their behavior along the food production chain
• Grantee: Emilie Lang
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• FAPESP's process: 19/16209-2 - Salmonella and Cronobacter sakazakii in milk and infant formula: behavior during spray drying and determination of inactivation parameters based on single droplet approach
• Grantee: Emilie Lang
• Support Opportunities: Scholarships in Brazil - Post-Doctoral