Unprecedented report: First female monozygotic twins as carriers of Hutchinson-Gilford progeria syndrome

Advanced search

Search - Use quotation marks to get a more specific result

Index

Field of knowledge

Start date

Betweenand

Full text
Author(s):	Reis-Filho, Nelson Carlos ; Aguiar, Thays Karolyne Ponte Prado ; Ramos, Dafnin Lima De Souza ; Mueller, Bruna Mariah Martins ; de Oliveira, Isadora Sousa ; Cerni, Felipe Augusto ; Pucca, Manuela Berto Total Authors: 7
Document type:	Journal article
Source:	TRENDS IN PEDIATRICS; v. 5, n. 2, p. 5-pg., 2024-06-30.
Abstract
Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic condition characterized by premature aging resulting from an autosomal mutation in the LMNA gene. This article presents a groundbreaking instance of the first female monozygotic twins affected by HGPS, originating from Brazil, highlighting the exceptional nature of this case. (AU)

FAPESP's process:	20/13176-3 - Human monoclonal antibodies (scFv) discovery with cross-reactivity and pH-dependent to metalloproteases from Bothrops spp
Grantee:	Isadora Sousa de Oliveira
Support Opportunities:	Scholarships in Brazil - Post-Doctoral