Organocatalytic Enantioselective Syntheses of Flavonoids and Cannabinoids

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Author(s):	Vidal-Albalat, Andreu ; Matos Paz, Bruno Total Authors: 2
Document type:	Journal article
Source:	ADVANCED SYNTHESIS & CATALYSIS; v. 366, n. 5, p. 12-pg., 2023-11-28.
Abstract
Flavonoids and cannabinoids comprise two large families of natural products that contain a chromane moiety in their structure. Their therapeutic potential has been extensively investigated as potential treatments to several diseases, ranging from cancer to infectious and neurodegenerative diseases. Despite their relative structural simplicity, in recent years creative synthetic methodologies were designed to overcome limitations from the previous synthetic strategies applied to these compounds. The aim of this review is to provide a comprehensive overview of all the enantioselective organocatalytic strategies that have been applied to the synthesis of flavonoids and cannabinoids to date. image (AU)

FAPESP's process:	22/14310-0 - Linear free energy relationships in asymmetric catalysis
Grantee:	Bruno Matos Paz
Support Opportunities:	Research Grants - Young Investigators Grants