City: São Caetano do Sul
See other companies with research projects supported by PIPE ProgramG-protein coupled receptors (GPCRs) are important pharmacological targets. Drugs that alter the activity of these receptors can have a therapeutic effect on several diseases, such as cardiovascular, psychological, and immunological diseases. Many drugs were created focusing on the modulation of specific GPCRs, blocking or stimulating their activity. In fact, around 35% of all FDA-approved…
The oxytocin receptor (OXTR) is a G protein-coupled receptor (GPCR) involved in the modulation of various signaling biological processes. Although its function was initially linked only to its role in the induction of labor and breastfeeding, its role in several other processes has recently been raised, specifically with regard to its potential use as a pharmacological target. OXTR agonis…
The neuropeptide oxytocin (OXT) acts as a neurotransmitter and neuromodulator in several physiological processes in humans and other mammals, among them we can mention: maternal behavior, food intake, social memory, sexual behavior, stress response, anxiolytic action and promotion of pro-social behavior of trust. Because it is involved in various physiological processes, the drug formulat…
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