Detection and Characterization of Enterovirus B73 from a Child in Brazil

Autor(es):Mostrar menos -

Ribeiro, Geovani de Oliveira ^[1] ; Luchs, Adriana ^[2] ; de Padua Milagres, Flavio Augusto ^{[3, 4, 5]} ; Komninakis, Shirley Vasconcelos ^{[6, 7]} ; Gill, Danielle Elise ^[8] ; Brito Sayao Lobato, Marcia Cristina Alves ^{[5, 7]} ; Brustulin, Rafael ^{[3, 5]} ; das Chagas, Rogerio Togisaki ^{[3, 5]} ; Neves dos Santos Abrao, Maria de Fatima ^{[3, 5]} ; de Deus Alves Soares, Cassia Vitoria ^{[3, 5]} ; Witkin, Steven S. ^{[8, 9]} ; Villanova, Fabiola ^[1] ; Deng, Xutao ^{[10, 11]} ; Sabino, Ester Cerdeira ^{[8, 12]} ; Delwart, Eric ^{[10, 11]} ; da Costa, Antonio Charlys ^[8] ; Leal, Elcio ^[1]

Afiliação do(s) autor(es):Mostrar menos -

^[1] Fed Univ Para, Inst Biol Sci, BR-66075000 Belem, Para - Brazil

^[2] Adolfo Lutz Inst, Virol Ctr, Enter Dis Lab, BR-01246000 Sao Paulo - Brazil

^[3] Secretary Hlth Tocantins, BR-77453000 Tocantins - Brazil

^[4] Fed Univ Tocantins, Inst Biol Sci, BR-77001090 Tocantins - Brazil

^[5] Publ Hlth Lab Tocantins State LACEN, BR-77016330 Tocantins - Brazil

^[6] Univ Fed Sao Paulo, Retrovirol Lab, BR-04023062 Sao Paulo - Brazil

^[7] Fac Med ABC, Postgrad Program Hlth Sci, BR-09060870 Santo Andre - Brazil

^[8] Univ Sao Paulo, Inst Trop Med, BR-05403000 Sao Paulo - Brazil

^[9] Weill Cornell Med, Dept Obstet & Gynecol, New York, NY 10065 - USA

^[10] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA 94143 - USA

^[11] Blood Syst Res Inst, San Francisco, CA 94143 - USA

^[12] Univ Sao Paulo, Fac Med, LIM 46, BR-01246903 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Viruses-Basel; v. 11, n. 1 JAN 2019.
• Citações Web of Science: 0

Resumo

Enterovirus B73 is a new member of the Enterovirus B species. First detected in the USA, it has been subsequently identified in China, India, Oman, and the Netherlands. In this study, we characterize the first B73 strain (named TO-127) to be detected in South America. TO-127 was obtained from a child with acute gastroenteritis living in a rural area in Northern Brazil. The subject was not infected with any known enteric pathogens such as norovirus, rotavirus, helminths, or enteric bacteria. Analysis of the nearly full-length TO-127 genome (6993 nt) indicated a 74-75% nucleotide similarity with EV-B73 strains from other countries. Evolutionary analysis suggests that B73 is endemic and widespread. (AU)

• Processo FAPESP: 15/12944-9 - Investigando a evolução de cepas animais de rotavírus infectando humanos
• Beneficiário: Adriana Luchs
• Linha de fomento: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/00021-9 - Metagenômica viral da dengue, Chikungunya e Zika: acompanhar, explicar e prever a transmissão e distribuição espaço-temporal no Brasil
• Beneficiário: Antonio Charlys da Costa
• Linha de fomento: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 16/01735-2 - Metagenômica viral de dengue, Chikungunya e Zika vírus: acompanhar, explicar e prever a transmissão e distribuição espaço-temporal no Brasil
• Beneficiário: Ester Cerdeira Sabino
• Linha de fomento: Auxílio à Pesquisa - Regular