Abstract
The analysis of proteins, from functional, structural and biochemical perspectives, has moved forward apace in recent decades. For example, the Protein Data Bank (established in 1971) now contains the structures of >130,000 proteins, derived using X-ray diffraction, NMR and electron microscopy, compared to approximately 10,000 in 1999. >97% (>126,000) of these structures are soluble prote…
