Virus
This page of Research Supported by FAPESP assembles referential information on scholarships and research grants, awarded by FAPESP, related to the research theme Virus.
The display board "FAPESP Support in Numbers" presents the amount of ongoing or concluded scholarships and research grants, awarded by the Foundation, related to the theme Virus. In the center of the page, you will see some information on scholarships and research grants for development in Brazil and abroad.
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Use the "Refine results" list of options to filter information on the research theme Virus and to get results that are more specific for your search, according to following parameters: Field of Knowledge, type of Research Grants, modality of Scholarships, type of Programs, Institution and status of Research Projects.
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- Natural sanitizer against nosocomial infection agents by Machaerium and Byrsonima, AP.R
Abstract
Hospital sanitation is responsible for ensuring that the environments in which vulnerable patients are located do not pose a risk to their health. Effective sanitation, however, is not easy to achieve. Around 50% of hospital surfaces were found to be contaminated, due to lapses in the effectiveness of the sanitizers currently used, which in addition to recontamination, can even induce mic…
- Activation of type VI secretion systems in clinical isolates of Stenotrophomonas maltophilia, AP.R
Abstract
Stenotrophomonas maltophilia is a widely distributed Gram-negative bacterium, considered an emerging, multidrug-resistant opportunistic pathogen, typically associated with nosocomial infections. Like other diderm (Gram-negative) bacteria, S. maltophilia possesses protein secretion systems-molecular machineries involved in transporting proteins (effectors) from the intracellular environmen…
- Profile of microRNAs from the C19MC and C14MC family involved in the regulation of antiviral and inflammatory response in placentas in Chikungunya and Oropouche infection, AP.R
Abstract
Viral infection during pregnancy can pose risks such as vertical transmission and serious consequences for the fetus. Prenatal infection with arboviruses such as chikungunya (CHIKV) can have serious consequences with neurological damage to the fetus. Oropouche virus (OROV), an emerging arbovirus, causes oropouche fever and recent reports in 2024 have identified cases of fetal death and se…
(Only some records are available in English at this moment)
- 16th International Symposium of Plant Virus Epidemiology, AO.R
- FAPESP Week France - Paris, AR.EXT
- FAPESP Week France - Paris, AR.EXT
(Only some records are available in English at this moment)
- Therapeutic Potential of Coumarins against hRSV: Search for mechanisms, targets of viral inhibition and modulation of the inflammatory response, BP.PD
Abstract
Human Respiratory Syncytial Virus (hRSV) is among the main causative agents of severe acute respiratory infections affecting the lower respiratory tract, especially in children under two years of age and the elderly, being responsible for the majority of pneumonia and bronchiolitis cases. The increasing number of infections poses a challenge for public health and society. Currently, treat…
- ANTIFUNGAL ACTIVITY OF PROPOLIS ON PLANKTONIC AND SESSILE CELLS OF Candida tropicalis., BP.IC
Abstract
Candida tropicalis is an important species that gives rise, among other conditions, to candidemia, and is characterized by its high associated mortality rate. It is considered one of the most virulent species of the genus, with a hallmark feature of C. tropicalis infections being the formation of biofilms on various surfaces of medical devices and implants, such as catheters, artificial h…
- Targeting the endoplasmic reticulum to characterize monkeypox disease., BP.PD
Abstract
Since the first report of monkeypox infection in 1970, increasing cases of human infection was reported and gained a worldwide concern in 2022, when monkeypox virus (MPXV) passed through the African borders and landed in non-endemic continents like America, Europe and Asia. In Brazil, monkeypox cases was reported during the 2022 outbreak, being the second most affected country in the worl…
(Only some records are available in English at this moment)
- Investigation of the role of tumor mutational signatures as an approach for VUS reclassification and to investigate high-risk patients for colorectal cancer, BP.DD
Abstract
Aim: The most common genes associated with hereditary colorectal cancer (CRC) and endometrial cancer (EC) predisposition syndromes are involved in DNA repair mechanisms. When altered, these genes generate specific patterns of somatic mutations known as tumor mutational signatures (TMS). Recent pioneering studies in the literature illustrate how identifying TMS in high-risk CRC (HR-CRC) pa…
- Phenotypic study of extracellular vesicles and their relationship with senescence in the context of COVID-19, BP.EVC
Abstract
Extracellular vesicles (EVs) are nanosized particles released by almost all cell types and are recognized as new tools for local and systemic intercellular communication. It has been demonstrated that EVs carry and transfer a wide variety of molecules, such as proteins, nucleic acids, microRNAs, messenger RNAs. These molecules may be involved in physiological functions, the pathology of …
- Training and application of molecular tests for the diagnosis of RSV and other respiratory viruses and their implications in epidemiological surveillance., BP.TT
(Only some records are available in English at this moment)
- The role and mechanism of gamma delta T cells in Mayaro virus infection, BE.EP.DD
Abstract
Mayaro virus (MAYV) is a neglected arthritogenic arbovirus endemic to Latin America and the Caribbean, with a high potential to lead to future epidemics. Mayaro causes Mayaro fever, an illness with debilitating symptoms, such as fever, headache, polyarthralgia, and in some cases, neurological complications. Recent studies and our preliminary data indicated that gamma delta T cells can pla…
- Optimization of Purification and Cryo-EM Structural Determination of the Flagellar Stator MotAB-FliL Complex in Leptospira interrogans, BE.EP.DD
Abstract
Leptospira interrogans is a highly motile spirochete bacterium and the causative agent of leptospirosis, a zoonotic disease with increasing global incidence. The flagellar motor of Leptospira is a complex nanomachine essential for motility and pathogenicity, driven by the interaction between rotor and stator units. The stator complex, composed of MotA, MotB, and FiIL proteins, plays a cru…
- Computational drug discovery on canonical and alternative sites of influenza polymerases, BE.EP.DD
Abstract
Current outbreaks of the highly-pathogenic avian influenza A H5N1 virus highlight the need for new antiviral therapies and pandemic preparedness. It is noteworthy that the viral influenza RNA polymerase comprises a valuable target for drug discovery. Its cap-binding domain on the PB2 subunit (PB2cap) is conserved among influenza viruses and involved in the "cap-snatching" mechanism that p…
(Only some records are available in English at this moment)
- Spatial prioritization of rabies zoonotic risk and applications for public health in Brazil, BE.EP.IC
Abstract
Economic activities in neotropical regions, particularly agricultural expansion, have led to highly fragmented landscapes, altering resources available to biodiversity and affecting species population dynamics. These environmental changes can influence species' success or decline, including the transmission of zoonotic diseases. Neotropical bats, particularly Desmodus rotundus, are impact…
- Phylodynamics, and Evolution of Influenza A/H1N1pdm09 in Brazil: Integrating Genetic, Epidemiological, and Temporal Data (2009-2024), BE.EP.PD
Abstract
This project aims to conduct a comprehensive phylodynamic analysis of the Influenza A/H1N1pdm09 virus in Brazil, spanning from 2009 to 2024. Influenza A viruses are significant public health threats, causing severe respiratory infections and resulting in substantial morbidity and mortality worldwide. The emergence of the A/H1N1pdm09 strain marked the first human influenza pandemic of the …
- Evaluation of Leptospira interrogans FecR proteins rLIC10902 and rLIC20185 interaction with human cells and heterologous expression in non-pathogenic Leptospira, BE.EP.MS
Abstract
Pathogenic L. interrogans is the main causative agent of leptospirosis, a worldwide spread spillover that infects approximately 1 million people per year. Leptospiral infection is intimately related to its outer membrane proteins (OMPs), since they are the first structures to interact with a host's molecules. Thus, the study of these proteins is extremely important to understanding the pa…
(Only some records are available in English at this moment)
| 235 / 229 | Ongoing grants |
| 2,872 / 1689 | Completed research grants |
| 564 / 564 | Ongoing scholarships in Brazil |
| 4,846 / 2886 | Completed scholarships in Brazil |
| 50 / 50 | Ongoing scholarships abroad |
| 454 / 406 | Completed scholarships abroad |
| 9,021 / 5824 | All research grants and scholarships |
| Associated processes | |
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