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Grant number: 17/24153-1
Support Opportunities:Regular Research Grants
Duration: February 01, 2019 - January 31, 2022
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal Investigator:Susana Morimoto
Grantee:Susana Morimoto
Host Institution: Universidade Ibirapuera (UNIB). Campus Chácara Flora. São Paulo , SP, Brazil
Associated researchers:Daniela Prócida Raggio ; Maria Stella Nunes Araujo Moreira ; Reinaldo Macedo Fraga ; Tamara Kerber Tedesco


Objective: To evaluate the immediate and mediate outcomes of endocrowns and onlay ceramic restorations with glass fiber pin in endodontically treated teeth. Material and methods: A randomized controlled clinical trial, a double-blind (patient and examiner) is conducted by two trained and calibrated operators who perform all restorative procedures. The restorations are evaluated longitudinally by a blind and calibrated examiner using the USPHS. A total of 20 patients will be randomly assigned to each group for a total of 40 patients. The randomization sequence will be generated ( and to ensure the confidentiality of the allocation, this will be used opaque, sealed and numbered envelopes in series. These will be kept with an independent researcher for the moment of inclusion of the subjects. In the group of onlays, the teeth receive a fiberglass pin in the main root canal and composite resin filling. In the group of endocrown, only the restoration fill the pulp chamber. The parts are milled in IPS e-max CAD (Ivoclar Vivadent) and cemented with the Multilink cementation system (Ivoclar Vivadent). The immediate clinical (focused in restoration and patient) and mediate (radiographic and clinical) outcomes will be compared between the groups. Survival and success rates will be defined in 6, 12 and 24 months. Survival will be established by Kaplan-Meier survival curve and log-rank can be conducted to identify as variables associated with as failures over time. Multivariate analysis with the Cox regression models will be condutcted for the determination of failure predictors. For all analyzes, the significance value will be adjusted to 5%. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MORIMOTO, SUSANA; FRAGA, REINALDO M.; TEDESCO, TAMARA KERBER; OZCAN, MUTLU; SAMPAIO, FLAVIA B. W. R.; RAGGIO, DANIELA P.. Two-Year Survival of Ceramic Endocrowns and Partial Coverage Ceramic Restorations with Fiber Post: A 2-Year Double-Blind Randomized Clinical Trial. EUROPEAN JOURNAL OF PROSTHODONTICS AND RESTORATIVE DENTISTRY, v. N/A, p. 10-pg., . (17/24153-1)
RAMALHO, JULIANA ALVES DA SILVA; PALMA, LUIZ FELIPE; RAMALHO, KAREN MULLER; TEDESCO, TAMARA KERBER; MORIMOTO, SUSANA. Effect of botulinum toxin A on pain, bite force, and satisfaction of patients with bruxism: A randomized single-blind clinical trial comparing two protocols. SAUDI DENTAL JOURNAL, v. 35, n. 1, p. 8-pg., . (17/24153-1)

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