Synthesis of Biomedicine Complexes and Characterization by means of Vibrational and Electronic Spectroscopy, and DFT Calulations

• Grant number: 19/00558-8
• Support Opportunities: Regular Research Grants
• Start date: April 01, 2019
• End date: March 31, 2020
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Principal Investigator: Claudio Alberto Tellez Soto
• Grantee: Claudio Alberto Tellez Soto
• Host Institution: Universidade Brasil. Campus São Paulo. São Paulo , SP, Brazil

Abstract

Our purpose is to analyze scientific and industrial problems to provide social benefits. We aim at synthesis and characterization of new biomedicine compounds that use barbiturates, isoniazid and amino acids as complexing ligands. We employ the graphical methodology to the syntheses and vibrational/electronic spectroscopy to characterize the compounds. The structural studies will be performed with calculations based on the Density Functional Theory. Our research is justified because it leads to the introduction of new compounds of medicinal interest, with beneficial impacts on society, as well as to provide the formation of human resources. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SOARES, ELIENE ANDRADE; TELLEZ, CLAUDIO; FORTES, SABRINA A.; COELHO, ANILTON; VERSIANE, OTAVIO; FERREIRA, GLAUCIO B.; ANTONIETA MONDRAGON, MARIA; TELLEZ, CLAUDIO A.. Fourier transform infrared and Raman spectra of the complex cation diethyldithiocarbamate Cr(III) Di-hydrate, [Cr(DDTC)(2)(OH2)(2)](+). UV-Vis spectrum, DFT:B3LYP/6-311G(d, p) structural determination, vibrational and natural bond orbital analysis. Journal of Molecular Structure, v. 1256, p. 11-pg., 2022-05-15. (19/00558-8)

TELLEZ-SOTO, CLAUDIO A.; SILVA, MICHELY G. PEREIRA; DOS SANTOS, LAURITA; MENDES, THIAGO DE O.; SINGH, PRIYANKA; FORTES, SABRINA A.; FAVERO, PRISCILA; MARTIN, AIRTON A.. In vivo determination of dermal water content in chronological skin aging by confocal Raman spectroscopy. VIBRATIONAL SPECTROSCOPY, v. 112, JAN 2021. (19/00558-8)

UEBELE, DANIELA T. R.; SOTO, CLAUDIO A. TELLEZ; GALVA, NIERLLY K. A. M.; TIM, CARLA R.; SOBRINHO, ARGEMIRO S. DA SILVA; PESSOA, RODRIGO S.; DOS SANTOS, LAURITA. Ozonizing sunflower oil using Fourier-transform infrared spectroscopy for product characterization. VIBRATIONAL SPECTROSCOPY, v. 123, p. 6-pg., 2022-11-09. (18/01265-1, 19/00558-8, 18/03517-8)