VIDA-FROG: valorization of molecules isolated from aquatic Portuguese amphibians

• Grant number: 18/07999-7
• Support Opportunities: Regular Research Grants
• Start date: May 01, 2019
• End date: December 31, 2022
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Agreement: Fundação para a Ciência e a Tecnologia (FCT)
• Principal Investigator: Massuo Jorge Kato
• Grantee: Massuo Jorge Kato
• Principal researcher abroad: Peter Jonathan Eaton
• Institution abroad: Universidade do Porto (UP), Portugal
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated researchers: José Roberto de Souza de Almeida Leite
• Associated scholarship(s): 19/27661-3 - Bioactive peptides from aquatic Portuguese amphibians, BP.PD

Abstract

The objective of this study is the integration of experiences in the identification and characterization of bioactive compounds (peptides from animal origin and secondary compounds from plants). Studies involving synergism between peptides and amides based on natural products may contribute to understand structure-activity relationship and to the describe biological processes involved in the control of microrganisms, parasites and cell growth. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BARROS, ANA L. A. N.; HAMED, ABDELAATY; MARANI, MARIELA; MOREIRA, DANIEL C.; EATON, PETER; PLACIDO, ALEXANDRA; KATO, MASSUO J.; LEITE, JOSE ROBERTO S. A.. he Arsenal of Bioactive Molecules in the Skin Secretion of Urodele Amphibian. FRONTIERS IN PHARMACOLOGY, v. 12, JAN 14 2022. (18/07999-7)

HAMED, ABDELAATY; YAMAGUCHI, LYDIA FUMIKO; MORANTE, ESTELA YNES VALENCIA; SPIRA, BENY; STAMMLER, HANS GEORG; EL GAAFARY, MENNA; ZIEGLER, DAVID; SYROVETS, TATIANA; SIMMET, THOMAS; KATO, MASSUO JORGE. Cannabinoid-like meroterpenoids from Peperomia incana. Phytochemistry, v. 207, p. 12-pg., 2023-01-12. (14/50316-7, 19/27661-3, 18/07999-7)

BARBOSA, EDER ALVES; PLACIDO, ALEXANDRA; MOREIRA, DANIEL C.; ALBUQUERQUE, LUCAS; DEMATEI, ANDERSON; SILVA-CARVALHO, AMANDDA E.; CABRAL, WANESSA F.; BAO, SONIA N.; SALDANHA-ARAUJO, FELIPE; KUCKELHAUS, SELMA A. S.; et al. The peptide secreted at the water to land transition in a model amphibian has antioxidant effects. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, v. 288, n. 1962, NOV 10 2021. (18/07999-7)