Multifunctional plataforms based on lanthanide doped nanostructured luminescent materials for potential photonic and theranostic applications

• Grant number: 20/05319-9
• Support Opportunities: Regular Research Grants
• Duration: September 01, 2020 - December 31, 2022
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
• Principal Investigator: Rogéria Rocha Gonçalves
• Grantee: Rogéria Rocha Gonçalves
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated scholarship(s): 22/05151-6 - Morphological and structural control study of lanthanide ions doped sodium tantalate nanoparticles, BP.TT; 22/05148-5 - Lanthanide doped calcium germanate: Synthesis, properties and applications, BP.TT; 21/04973-0 - Hollow and porous spheres of rare earth doped yttrium silicate: synthesis and properties, BP.TT; 21/04985-8 - Development of lanthanide doped gadolinium niobate based luminescent materials, BP.TT

Abstract

The development of luminescent nanostructured materials doped with lanthanide ions, whether in the form of particulate material or films represents the objective of this project, specifically targeting the spectroscopic study of inorganic materials with efficient emission in the near infrared (IR) and in the visible for applications in Photonics and Theranostics. The control of the morphological and structural properties of oxides and fluorides and their correlation with optical and luminescent properties represent the academic and scientific basis of this project, aiming at applications that support the technological and innovation basis of the project in the following strategic areas: health, with development multifunctional platforms for dual application in theranostics (biomarkers and energy converters for photo-activation of molecules used in photodynamic therapy); telecommunications, with the development of optical amplifiers for telecommunications systems with broadband operation; mining and environmental: use of national mining precursors and e-waste recycling product; energy converters: development of new materials for the generation of white light and photoconversion.The materials (waveguides or particulates) will be prepared for more than one functionality, which we are calling multifunctional platforms. Original results with potential application have been previously synthesized by our research group (see results from previous projects); and this project aims to study the structural, optical and spectroscopic properties in nanocomposite films derived from SiO2 and GeO2 prepared via sol-gel for application in photonics as optical amplifiers, working in telecommunications. The project aims to develop materials with broadband emission in the near infrared (IV) region. Systems based on 1-xSiO2-xM2O5, 1-xGeO2-xM2O5 (M = Ta, Nb) and 1-xSiO2-xMO2, 1-xGeO2-xMO2 (M = Ti, Zr, Hf) will be studied focusing on the optical and spectroscopic as a function of the composition and concentration of the lanthanide doping ions (Eu3 + / Er3 + / Yb3 + / Tm3 + / Nd3 + / Pr3 + / Ho3 +). The correlation between optical and structural properties will be performed depending on the composition, method of synthesis, as well as the concentration of Ln3 + ions. The co-doping of these nanocomposite systems will be carried out aiming at the study of energy transfer processes and the dynamics of the mechanisms involved, in order to obtain materials with efficient emission in the IV (broadband). The choice of the matrix containing GeO2 aims at higher transparency in the region IV and exploration of photosensitive properties for the preparation of microstructures with incidence of light.Studies on the up conversion dynamics in nanostructured oxide systems of relatively low phonon energy, and specifically tantalates, niobates, hafnates, zirconates, titanates and stannates, doped with lanthanide ions, will be continued, especially since they are compounds with high solubility of lanthanide ions. Rare earth oxides (Y2O3, Gd2O3) and rare earth fluorides will be synthesized, aiming at the optimization of systems with potential application as optical markers and as efficient energy converters, with emission in the visible and IV after excitation in the IV, in order to use the biological transparency windows and deeper layers of the human body. The luminescent particles will be conjugated to compounds of coordination of ruthenium and protoporphyrin IX, aiming at both optical marking and treatment of neoplasms using photodynamic therapy. In a later stage, the encapsulation in nanocarriers will be carried out aiming at dispersion in biological media, biocompatibility, as well as the conjugation with molecules and allowing the permeation in the blood-brain barrier. Valorization of national mining products and recycling of electronic waste will be used in alternative synthesis routes. (AU)

Scientific publications

(22)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FALEIRO, JOSE HENRIQUE; DANTAS, NOELIO O.; SILVA, ANIELLE C. A.; BARBOSA, HELLIOMAR P.; DA SILVA, BRUNO H. S. T.; LIMA, KARMEL DE O.; GONCALVES, ROGERIA ROCHA; FERRARI, JEFFERSON LUIS. Niobium oxide influence in the phosphate glasses triply doped with Er3+/ Yb3+/Eu3+ prepared by the melting process. Journal of Non-Crystalline Solids, v. 571, NOV 1 2021. (18/18213-4, 20/05319-9)

CAIXETA, FABIO JOSE; AQUINO, FELIPE THOMAZ; PEREIRA, RAFAEL RAMIRO; GONCALVES, ROGERIA ROCHA. Highly red luminescent Nb2O5:Eu3+ nanoparticles in silicate host for solid-state lighting and energy conversion. Optical Materials, v. 111, JAN 2021. (20/05319-9, 17/11301-2, 17/10423-7)

NUNES, L. R. R.; LABAKI, H. P.; CAIXETA, F. J.; GONCALVES, R. R.. Yb3+ influence on NIR emission from Pr3+-doped spherical yttria nanoparticles for advances in NIR I and NIR II biological windows. Journal of Luminescence, v. 241, JAN 2022. (20/05319-9, 19/25991-6, 17/10423-7)

BORGES, FERNANDA HEDIGER; MARTINS, JOANA COSTA; CAIXETA, FABIO JOSE; CARLOS, LUIS D.; FERREIRA, RUTE A. S.; GONCALVES, ROGERIA ROCHA. Luminescent thermometry based on Er3+/Yb3+ co-doped yttrium niobate with high NIR emission and NIR-to-visible upconversion quantum yields. Journal of Luminescence, v. 248, p. 10-pg., 2022-08-01. (17/11301-2, 20/05319-9, 20/00277-6, 17/10424-3, 18/04587-0)

DOS SANTOS, L. F.; MARTINS, J. C.; LIMA, K. O.; GOMES, L. F. T.; DE MELO, M. T.; TEDESCO, A. C.; CARLOS, L. D.; FERREIRA, R. A. S.; GONCALVES, R. R.. In vitro assays and nanothermometry studies of infrared-to-visible upconversion of nanocrystalline Er3+,Yb3+ co-doped Y2O3 nanoparticles for theranostic applications. PHYSICA B-CONDENSED MATTER, v. 624, JAN 1 2022. (18/18213-4, 17/10440-9, 18/04588-6, 20/05319-9)

MANFRE, MATEUS GRECCO; GONCALVES, ROGERIA ROCHA. Lanthanide-doped niobium oxide nanoparticles on nanoarchitectured silica spheres as potential probe for NIR luminescent markers. Journal of Luminescence, v. 252, p. 13-pg., 2022-12-01. (17/11301-2, 20/05319-9)

REZENDE, THAIS KARINE DE LIMA; BARBOSA, HELLIOMAR PEREIRA; LIMA, KARMEL DE OLIVEIRA; GOES, MARCIO SOUSA; DE LIMA, RENATA CRISTINA; GONCALVES, ROGERIA ROCHA; FERRARI, JEFFERSON LUIS. Simultaneous excitation at IR and UV of RE3+ triply doped SiO2-Gd2O3 materials for energy conversion purposes. CERAMICS INTERNATIONAL, v. 47, n. 24, p. 35187-35200, DEC 15 2021. (20/05319-9, 18/18213-4)

MANFRE, MATEUS GRECCO; LABAKI, HAYRA DO PRADO; DE SOUZA, VITOR DOS SANTOS; GONCALVES, ROGERIA R.. Red and near-infrared emitting phosphors based on Eu3+- or Nd3+-doped lanthanum niobates prepared by the sol-gel route. DALTON TRANSACTIONS, v. 51, n. 46, p. 14-pg., 2022-10-31. (21/08111-2, 20/05319-9)

FALEIRO, JOSE HENRIQUE; DANTAS, NOELIO O.; SILVA, ANIELLE C. A.; BARBOSA, HELLIOMAR P.; SILVA, BRUNO H. S. T. DA; LIMA, KARMEL DE O.; SILVA, GUILHERME DE FREITAS; GONSALVES, ROGERIA ROCHA; FALCI, RODRIGO; MESSADEQ, YOUNES; et al. Niobium incorporation into rare-earth doped aluminophosphate glasses: Structural characterization, optical properties, and luminescence. Journal of Non-Crystalline Solids, v. 605, p. 11-pg., 2023-02-02. (20/05319-9, 13/07793-6, 19/26399-3, 18/18213-4)

PESSOA, ALLISON R.; GALINDO, JEFFERSON A. O.; DOS SANTOS, LUIZ F.; GONCALVES, ROGERIA R.; MAIER, STEFAN A.; MENEZES, LEONARDO DE S.; AMARAL, ANDERSON M.. Correction Due to Nonthermally Coupled Emission Bands and Its Implications on the Performance of Y2O3:Yb3+ /Er3+ Single-Particle Thermometers. Journal of Physical Chemistry C, v. 127, n. 20, p. 8-pg., 2023-05-16. (17/11301-2, 20/04157-5, 20/05319-9, 21/08111-2)

FERRARI, JEFFERSON L.; LIMA, KARMEL DE O.; GONCALVES, ROGERIA R.. Refractive Indexes and Spectroscopic Properties to Design Er3+-Doped SiO2-Ta2O5 Films as Multifunctional Planar Waveguide Platforms for Optical Sensors and Amplifiers. ACS OMEGA, v. 6, n. 13, p. 13-pg., 2021-03-25. (20/05319-9, 18/18213-4)

DA CUNHA, CRISTIANO RAMOS; MARCONDES, LIA MARA; BATISTA, GISLENE; GONCALVES, ROGERIA ROCHA; CASSANJES, FABIA CASTRO; POIRIER, GAEL YVES. rystallization of bronze-like perovskite in potassium tantalum germanate glasses: Glass ceramic preparation and its optical propertie. Optical Materials, v. 122, n. B, DEC 2021. (20/01786-1, 17/11301-2, 20/05319-9)

MARQUES DE SOUZA, JOACILIA MAZZINI; LIMA, KARMEL DE OLIVEIRA; FERRARI, JEFFERSON LUIS; QUEIROZ MAIA, LAURO JUNE; GONCALVES, ROGERIA ROCHA; FALCI, RODRIGO FERREIRA; MANZANI, DANILO. hotoluminescence properties of Er3+ and Er3+/Yb3+ doped tellurite glass and glass-ceramics containing Bi2Te4O11 crystal. DALTON TRANSACTIONS, v. 51, n. 10, p. 4087-4096, MAR 8 2022. (18/18213-4, 20/05319-9, 18/16407-6)

LIMA, KARMEL DE OLIVEIRA; DOS SANTOS, LUIZ FERNANDO; GALVAO, RODRIGO; TEDESCO, ANTONIO CLAUDIO; MENEZES, LEONARDO DE SOUZA; GONCALVES, ROGERIA ROCHA. Single Er3+, Yb3+: KGd3F10 Nanoparticles for Nanothermometry. FRONTIERS IN CHEMISTRY, v. 9, JUL 21 2021. (20/05319-9, 17/11301-2, 17/10440-9, 18/18213-4)

LIMA, KARMEL DE OLIVEIRA; DOS SANTOS, LUIZ FERNANDO; DE MELO, MARYANNE TRAFANI; TEDESCO, ANTONIO CLAUDIO; GONCALVES, ROGERIA ROCHA; GREDIN, PATRICK; MORTIER, MICHEL. Highly colloidal luminescent Er3+, Yb3+-codoped KY3F10 nanoparticles for theranostic applications. MATERIALS TODAY COMMUNICATIONS, v. 28, SEP 2021. (18/18213-4, 20/05319-9, 17/11301-2)

MARCONDES, LIA MARA; DA CUNHA, CRISTIANO RAMOS; DE PIETRO, GABRIELE MATINATTI; MANZANI, DANILO; GONCALVES, ROGERIA ROCHA; BATISTA, GISLENE; CASSANJES, FABIA CASTRO; POIRIER, GAEL. Multicolor tunable and NIR broadband emission from rare-earth-codoped tantalum germanate glasses and nanostructured glass-ceramics. Journal of Luminescence, v. 239, NOV 2021. (20/01786-1, 17/11301-2, 18/16126-7, 13/07793-6, 20/05319-9)

LIMA, KARMEL DE OLIVEIRA; CAIXETA, FABIO JOSE; DE SOUZA, VITOR DOS SANTOS; ROSA, LEONARDO SOUSA; SOARES, VICTOR DEL VECCHIO; CRUMO, CAROLINA ASSUNCAO; BORIN, IVANA APARECIDA; FERRARI, JEFFERSON LUIS; GONCALVES, ROGERIA ROCHA. Super Broadband at Telecom Wavelengths From RE3+-Doped SiO2-Ta2O5 Glass Ceramics Planar Waveguides. RONTIERS IN CHEMISTR, v. 10, p. 12-pg., 2022-07-04. (20/05319-9, 17/10423-7, 18/18213-4)

LABAKI, H. P.; BORGES, F. H.; CAIXETA, F. J.; GONCALVES, R. R.. Widely dual tunable visible and near infrared emission in Pr3+-doped yttrium tantalate: Pr3+ concentration dependence on radiative transitions from P-3(0) to the D-1(2). Journal of Luminescence, v. 236, AUG 2021. (20/05319-9, 17/10423-7, 19/25991-6, 18/04587-0, 17/10424-3)

LABAKI, HAYRA DO PRADO; CAIXETA, FABIO JOSE; GONCALVES, ROGERIA ROCHA. Wide multicolor tunability of blue-to-green up-conversion emission and white light generation in Pr3+/Yb3+ co-doped yttrium tantalates. Journal of Luminescence, v. 245, p. 11-pg., 2022-05-01. (20/05319-9, 17/10423-7, 19/25991-6)

DOS SANTOS, LUIZ F.; GALINDO, JEFFERSON A. O.; LIMA, KARMEL DE O.; PESSOA, ALLISON R.; AMARAL, ANDERSON M.; MENEZES, LEONARDO DE S.; GONCALVES, ROGERIA R.. Lifetime-based luminescence thermometry from Yb3+/Er3+codoped nanoparticles suspended in water. Journal of Luminescence, v. 262, p. 9-pg., 2023-05-31. (20/05319-9, 20/04157-5)

OLIVEIRA GALINDO, JEFFERSON AUGUSTO; PESSOA, ALLISON RODRIGO; AMARAL, ANDERSON MONTEIRO; DOS SANTOS, LUIZ F.; GONCALVES, ROGERIA R.; DE SOUZA MENEZES, LEONARDO. Influence of the surrounding medium on the luminescence-based thermometric properties of single Yb3+/Er3+ codoped yttria nanocrystals (vol 3, pg 6231, 2021). NANOSCALE ADVANCES, v. 3, n. 24, p. 1-pg., 2021-11-17. (20/05319-9)

DE SOUZA, VITOR DOS SANTOS; CAIXETA, FABIO JOSE; LIMA, KARMEL DE OLIVEIRA; GONCALVES, ROGERIA ROCHA. Modulating white light emission temperature in Ho3+/Yb3+/Tm3+ triply doped nanostructured GeO2-Nb2O5 materials for WLEDs applications. Journal of Luminescence, v. 248, p. 11-pg., 2022-08-01. (20/05319-9)