New process for stereoselective synthesis of cannabidiol

• Grant number: 20/05522-9
• Support Opportunities: Research Grants - Innovative Research in Small Business - PIPE
• Start date: April 01, 2021
• End date: December 31, 2021
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Manoel Trindade Rodrigues Junior
• Grantee: Manoel Trindade Rodrigues Junior
• Company: NFM Chemical Tecnology Ltda
• CNAE: Fabricação de produtos farmoquímicos
• Pesquisadores principais: Neide Montesano
• Associated researchers: Fernando Antonio Santos Coelho
• Associated scholarship(s): 21/03770-8 - New process for stereoselective synthesis of cannabidiol, BP.PIPE

Abstract

This project consists of a proposal of a new process for the stereoselective preparation of cannabidiol (CBD-Figure 1) catalyzed by Lewis acid. This substance of natural origin is one of the components of the Cannabis sativa plant extract, which unlike (-) - trans-9-tetrahydrocannabinol (THC), is a non-psychoactive phytocannabinoid. The interest in this project is due to the effectiveness of cannabidiol as a therapeutic agent in numerous pathological conditions. (AU)