Understanding bone remodeling and the effect of photobiomodulation during tooth movement in mature adults x young adults

• Grant number: 20/05795-5
• Support Opportunities: Regular Research Grants
• Start date: July 01, 2021
• End date: December 31, 2023
• Field of knowledge: Health Sciences - Dentistry - Orthodontics
• Principal Investigator: Aguinaldo Silva Garcez Segundo
• Grantee: Aguinaldo Silva Garcez Segundo
• Host Institution: Centro de Pesquisas Odontológicas São Leopoldo Mandic. Faculdade São Leopoldo Mandic (SLMANDIC). Sociedade Regional de Ensino e Saúde S/S Ltda (SRES). Campinas , SP, Brazil
• Associated researchers: Chooryung Chung ; Lucas Novaes Teixeira ; Marcelo Henrique Napimoga ; Martha Simões Ribeiro ; Selly Sayuri Suzuki

Abstract

Although age is not a contraindication for orthodontic treatment, treating mature adult patients can be considered more challenging, mainly due to less responsive bone metabolism and reduced osteoblastic activity compared to young adult patients. In Orthodontics, photobiomodulation has shown positive results in bone remodeling during tooth movement, stimulating both bone resorption and bone formation processes. Currently, there is a lack of clinical studies targeting adult patients on the age of 40-60 years, as well as a lack of clinical recommendation and supporting therapeutic approaches to treat periodontally healthy or compromised patients. For this reason, orthodontic treatment in these individuals is commonly seen as limited. The present study aims to evaluate the effect of photobiomodulation on bone remodeling by inducing bone formation in mature adult patients and, therefore, allowing a better periodontal condition in order to obtain a more comprehensive correction of occlusal disorders and to satisfy patient's aesthetic request. (AU)