Eco engineering of nano-enabled plant protection technologies (ORGANIC)

• Grant number: 22/03399-0
• Support Opportunities: Regular Research Grants
• Start date: December 01, 2022
• End date: November 30, 2026
• Field of knowledge: Biological Sciences - Biochemistry - Chemistry of Macromolecules
• Agreement: ANR
• Principal Investigator: Renata de Lima
• Grantee: Renata de Lima
• Principal researcher abroad: Catherine Santaella
• Institution abroad: Institut de Biosciences et Biotechnologies d’Aix-Marseille (BIAM), France
• Host Institution: Pró-Reitoria de Pós-Graduação, Pesquisa, Extensão e Inovação. Universidade de Sorocaba (UNISO). Sorocaba , SP, Brazil
• Associated researchers: Claudemir Zucareli ; Daiana Silva de Ávila ; Halley Caixeta de Oliveira ; Leonardo Fernandes Fraceto ; Maria Isabel Balbi Pena ; Mariana Guilger Casagrande ; Ricardo Antonio Polanczyk
• Associated research grant(s): 24/01693-4 - Essential oils carried by silica nanoparticles to combat pathogens and pests., AP.R

Abstract

How to sustainably feed 10 billion people by 2050? Agriculture relies on agrochemicals to control pests and increase yields. Brazil ranks 44th and France 48th on pesticides (United Nations Food and Agriculture Organization). Fertilizers pollute rivers, groundwater, promote eutrophication and air pollution. Pesticides cause 355,000 deaths yearly by overexposure/misuse and affect non-target wildlife and biodiversity. Recent advances have unraveled the roles of small extracellular vesicles (50-500 nm) produced by plants and bacteria as an adaptive toolbox to manipulate microbe-plant interactions. Plant and microorganisms also synthesize biogenic inorganic nanoparticles (BINs) with varied activities. Overall, these nano-sized carriers of active molecules are inspiring models to develop Nature- and bio-based solutions enabled by Nanotechnologies to tackle sustainability in plant protection. Smart nanopesticides have new or enhanced properties and can deliver the active ingredient upon environmental stimuli. The nano aspect can concern the active ingredient and/or the carrier. The project aims to design smart nano-enabled phytoprotection strategies, with less impact on off-targets. Brazil and France teams will combine multidisciplinary expertise to develop safer-by-design solutions based on plant/microorganisms BINs and ecofriendly biopolymers-metal hybrids nanoparticles (HNP) to develop sustainable alternatives for crop protection. The team will cooperatively design, synthesize the new NPs, analyze the interaction mechanisms with plants and the impact on off-targets, as human cell lines, plants, nematodes, soil and plant microbiota, soil fertility, and the aquatic ecosystem. Taking advantage of a panel of different surfaces NPs in BINs and HNPs, we will explore the relationships between properties and impact/fate of nanocarriers in the plant-soil ecosystem. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

RODRIGUES, JESSICA S.; TAKESHITA, VANESSA; CAMPOS, ESTEFANIA V. R.; DE FREITAS, AMANDA S. M.; DE LIMA, VITOR H.; FRACETO, LEONARDO F.. Lignocellulosic Biomass in Nanopesticides: A Path toward Sustainable Agriculture. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, v. 12, n. 27, p. 23-pg., 2024-06-22. (17/21004-5, 22/03399-0, 21/10639-5, 19/04758-1, 22/00509-0, 23/00335-4)

CAMARGO, JESSICA ROCHA; ORZARI, LUIZ OTAVIO; RODRIGUES, JESSICA DE SOUZA; DE LIMA, LUCAS FELIPE; PAIXAO, THIAGO REGIS LONGO CESAR; FRACETO, LEONARDO FERNANDES; JANEGITZ, BRUNO CAMPOS. Advancements in disposable electrochemical systems for sustainable agriculture monitoring: Trends, gaps, and applied examples. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 180, p. 14-pg., 2024-09-13. (17/21004-5, 22/03399-0, 21/10639-5, 19/04758-1, 19/23342-0, 23/12589-0, 23/00246-1, 23/06793-4, 19/23177-0, 22/00509-0, 23/00335-4)

PROENCA, PATRICIA LUIZA DE FREITAS; CAMPOS, ESTEFANIA VANGELIE RAMOS; COSTA, TAIS GERMANO; DE LIMA, RENATA; PREISLER, ANA CRISTINA; DE OLIVEIRA, HALLEY CAIXETA; DA ROCHA, CLAUDIANE MARTINS; DE ANDRADE, DANIEL JUNIOR; GONCALVES, KELLY CRISTINA; POLANCZYK, RICARDO ANTONIO; et al. Curcumin and carvacrol co-loaded zein nanoparticles: Comprehensive preparation and assessment of biological activities in pest control. PLANT NANO BIOLOGY, v. 8, p. 11-pg., 2024-04-13. (17/21004-5, 22/03399-0, 21/10639-5, 23/14102-1, 22/00509-0)

MESAS, FLORENCIA ANABEL; MENDIETA, JULIETA RENEE; NICOLINI, ANDRES TORRES; DE OLIVEIRA, JHONES LUIZ; GERMANO-COSTA, TAIS; BILESKY-JOSE, NATALIA; DE LIMA, RENATA; FRACETO, LEONARDO FERNANDES; ALVAREZ, VERA ALEJANDRA; TERRILE, MARIA CECILIA. Deciphering physical and functional properties of chitosan-based particles for agriculture applications. International Journal of Biological Macromolecules, v. 285, p. 11-pg., 2024-12-04. (21/10639-5, 22/03399-0, 17/21004-5)