Evaluation of zirconia reinforced lithium silicate single crowns fabricated in CAD/CAM system: split-mouth randomized controlled clinical trial

• Grant number: 23/02207-3
• Support Opportunities: Regular Research Grants
• Start date: June 01, 2023
• End date: May 31, 2025
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Ana Flávia Sanches Borges
• Grantee: Ana Flávia Sanches Borges
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil
• Associated researchers: Adilson Yoshio Furuse ; Diana Gabriela Soares dos Passos ; Paulo Francisco Cesar ; S K Sidhu ; Sergio Kiyoshi Ishikiriama
• Associated research grant(s): 23/08019-4 - Multi-user Equipment approved in grant 23/02207-3: CEREC Primescan Connect, AP.EMU
• Associated scholarship(s): 24/16819-3 - Effectiveness of shade selection using the primescan intraoral scanner for communication with the prosthetic laboratory: comparison of accuracy and precision with visual and spectrophotometric methods, BP.MS

Abstract

The advancement of dental materials and their processing have been replaced posterior metal-ceramic crowns for metal free ceramic crowns. Ceramic restorations show color similar to the dental structure, as well as, absence of grayish margins, which fits the high esthetic requirement of patients. Ceramic crowns have shown good clinical performance, with success rates comparable to metal-ceramic prostheses. However, some clinical problems are still not fully elucidated. In addition, there are few clinical studies about the performance of ceramic crowns confectioned by CAD/CAM system with zirconia reinforced lithium silicate (ZRLS) and concerning dental wear evaluation by intra oral scanners data. Therefore, this research aims to validate the clinical viability of the use of ZRLS for single crowns, in order to verify their real advantages and disadvantages by a split-mouth randomized controlled clinical trial. Two ceramic compostions will be evaluated: monolithic single crowns of SLRZ and lithium disilicate (DL), seated in posterior teeth. The sample size will be of 50 participants or less, with each participant receiving two posterior crows or multiples of two, totaling 100 crowns, 50 of each material. The crowns will be analyzed by two blind independent calibrated evaluators, following USPHS criteria. The evaluation will be conducted in the baseline, 6 months and then 1, 2, 3 until 10 years. Success and survival rate will be estimated by Cox regression analysis, considering an interval of 95% of reliability. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FERRAIRO, BRUNNA M.; DE AZEVEDO-SILVA, LUCAS JOSE; MINIM, PEDRO R.; MONTEIRO-SOUSA, RAPHAELLE S.; PEREIRA, LETICIA F.; BITENCOURT, SANDRO B.; CESAR, PAULO FRANCISCO; SIDHU, SHARANBIR K.; BORGES, ANA FLAVIA S.. Biomechanical consideration in tooth-supported glass-ceramic restorations: A systematic review and meta-analysis of survival rates and irreparable failures. JOURNAL OF PROSTHETIC DENTISTRY, v. 132, n. 5, p. 13-pg., 2024-11-01. (23/08179-1, 23/02207-3)