Metagenomics to study the microbiome of feedlot cattle: relationships with feed efficiency and production traits

• Grant number: 24/09866-5
• Support Opportunities: Regular Research Grants
• Start date: October 01, 2024
• End date: February 28, 2026
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Animal Production
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Welder Angelo Baldassini
• Grantee: Welder Angelo Baldassini
• Principal researcher abroad: Pedro Henrique Vilela Carvalho
• Institution abroad: Colorado State University, United States
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
• Associated research grant: 23/05002-3 - Application of omics tools to study performance, carcass and meat quality traits of feedlot cattle: omics integration using "from-farm-to-fork" concept, AP.R

Abstract

Fecal microbiome provides insights into the efficiency of feed utilization, serving as a non-invasive indicator of rumen health and function. By assessing the composition and activity of fecal microbes, we can evaluate feed digestibility, identify microbial markers for efficient nutrient absorption, and develop tailored feeding strategies. Metagenomics, which involves the study of genetic material from environmental samples, is a powerful tool for investigating the fecal microbiome of cattle. In response to this, a collaborative project between Dr. Pedro Carvalho at Colorado State University (CSU) and Dr. Welder Baldassini at São Paulo State University (UNESP) aims to achieve high-resolution profiles of fecal microbiomes from beef cattle in feedlot systems, enhancing understanding of microbial community composition and function. Detailed metagenomic analyses will highlight differences influenced by diet, management practices, and production traits. Such information cam be used to identify microbial markers and pathways linked to enhanced feed efficiency (FE) and productivity. These insights will help develop guidelines for optimizing feedlot management, improving cattle health, and boosting efficiency. The joint research will focus on studying the fecal microbiome of beef cattle in feedlot systems, aiming to provide a detailed understanding of microbial communities and their functional potential. This collaboration will drive innovation in metagenomics, contributing to optimized cattle diets, enhanced productivity, and reduced greenhouse gas emissions. (AU)