Characterization of Low Pathogenicity Avian Influenza Viruses (LPAIVs) in the Americas

• Grant number: 25/02989-7
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2025
• End date: July 31, 2027
• Field of knowledge: Biological Sciences - Microbiology - Applied Microbiology
• Mobility Program: SPRINT - Projetos de pesquisa - Mobilidade
• Principal Investigator: Helena Lage Ferreira
• Grantee: Helena Lage Ferreira
• Principal researcher abroad: Miriã Ferreira Criado
• Institution abroad: Auburn University, United States
• Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
• Associated researchers: Edison Luiz Durigon
• Associated research grant: 22/08528-3 - Adjusting the active surveillance in migratory wild birds in the state of São Paulo, AP.PP

Abstract

The PPPP project associated with this proposal aims to identify sites at the interface of wild aquatic birds and backyard poultry that may increase the risk of avian influenza virus (AIV) transmission to commercial flocks in São Paulo. Preliminary findings identified a 3.5% seroprevalence of low pathogenic AIV in backyard birds and high-risk areas identified through kernel density analysis. The project seeks to enhance understanding of low pathogenic avian influenza (LPAI) circulation, assess viral pathogenicity, and mitigate animal and human health risks, supporting sustainable collaboration between institutions from Brazil and USA. (AU)