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Molluscicidal effect of 17 Piperaceae species extracts on Biomphalaria glabrata (Say, 1818)

Grant number: 98/06326-3
Support type:Regular Research Grants
Duration: September 01, 1998 - August 31, 2002
Field of knowledge:Biological Sciences - Parasitology - Entomology and Malacology of Parasites and Vectors
Principal researcher:Toshie Kawano
Grantee:Toshie Kawano
Home Institution: Instituto Butantan. Secretaria da Saúde (São Paulo - Estado). São Paulo , SP, Brazil


Extract from leaves and roots of Piperaceae species will be scored and tested to adults and eggmasses at the different stages of the development of Biomphalaria glabrata: first cleavages (0-15h after first cleavage), gástrula (24-30h), young trochophore (48-54h), trochophore (72-78h), young veliger (96-112h). Following parameters will be analysed: mortality, embryonic malformation and from each active substancies will be calculated the CL50. Selected active extracts will be dereplicated by chromatographic and spectroscopic techniques looking at determination of active compounds. (AU)

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