Biorrational control of insect pests

• Grant number: 08/57859-5
• Support Opportunities: Research Projects - Thematic Grants
• Duration: March 01, 2009 - June 30, 2014
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Convênio/Acordo: CNPq - INCTs
• Principal Investigator: Maria Fátima das Graças Fernandes da Silva
• Grantee: Maria Fátima das Graças Fernandes da Silva
• Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Associated scholarship(s): 11/19148-2 - Study of Lasiodiplodia theobromae as pathogen in Khaya ivorensis and search for secondary metabolites for the control of the fungus, BP.PD; 11/00970-4 - Nano and micro particles from Meliaceae extracts for pest control using lignin from sugarcane, BP.DR; 11/01334-4 - Nanocoated methylpheophorbiyde-a porphyrin and its use as an inhibitor for the photosynthetic reaction., BP.IC; + associated scholarships 10/10418-4 - Chemical study of Spodoptera frugiperda on metabolization of some activity compounds from Trichilia pallida, T. pallens and Toona ciliata, BP.DR; 10/10477-0 - Chemical study of insecticidal action (translaminar, systemic and topic) of Neem oil and their nanocapsules on Bemisia tabaci (Genn.) biotipo B in tomato plants, BP.DR; 09/16934-7 - Chemical study of Guignardia citricarpa pathogenic of Citrus genus., BP.IC - associated scholarships

Abstract

The effective control of insects and the search for biologically active compounds, which are closely related to the survival of human beings, are important aspects to be studied. The insects are the major competitors of man with respect to food, besides to be vectors of many diseases that affect human beings, herds, as well as to plants too. Considerable efforts have been made to produce natural compounds not toxic, especially to humans, which could biorationally control the behavior of pests, as well as to control diseases. This project aims to undertake studies to biorationally control the pest insects [Atta sexdens rubropilosa (Leaf-cutting ants), Spodoptera frugiperda (corn fall army worm), Diaphorina citri (Hemiptera: Psyllidae) of citrus, Microhymenopteran (common name Cigarrinhas) of Cicadellidae family (Dilobopterus costalimai, Acrogonia citrina e Scopogonalia subolivacea) and Cinara pinivora (common name pulgão-gigante-do-pinus)], through the use of plants; its extracts or isolated compounds; of semiochemicals; derived from natural products or semi-synthetic and actions on the associated microorganisms (fungi, bacteria and yeast). In this research project is also being proposed to build a network of collaboration among researchers from various Federal and State Universities and Research Institutes in order to foster the research involving the application of natural products and the identification and use of semiochemicals for the control and monitoring the population of pest insect of agriculture and silviculture. For its development will be used the state of art knowledge on (High Throughput Screening, NMR, Nanotechnology, Metabolomics, Bioreactors, among others), based on the experience of the team members in an effort to achieve the objectives of this project. (AU)

Scientific publications

(19)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

OLIVEIRA, REGINA M. M.; DE SOUZA DANIEL, JULIANA F.; CARLOS, ROSE M.. Synthesis, spectroscopic characterization and biological activity of cis-[Ru(hesperidin)(1,10 `-phenanthroline)(2)](PF6) complex. Journal of Molecular Structure, v. 1031, p. 269-274, JAN 16 2013. (09/08218-0, 08/57859-5)

GIONGO, A. M. M.; VENDRAMIM, J. D.; FREITAS, S. D. L.; SILVA, M. F. G. F.. Toxicity of Secondary Metabolites from Meliaceae Against Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae). Neotropical Entomology, v. 45, n. 6, p. 725-733, DEC 2016. (10/10418-4, 08/57859-5)

GARCIA, PAMELA SOTO; DARIO MOREAU, ALBERTO LUIS; MAGALHAES IERICH, JESSICA CRISTIANE; ARAUJO VIG, ANA CAROLINA; HIGA, AKEMI MARTINS; OLIVEIRA, GUEDMILLER S.; ABDALLA, FABIO CAMARGO; HAUSEN, MOEMA; LEITE, FABIO L.. A Nanobiosensor Based on 4-Hydroxyphenylpyruvate Dioxygenase Enzyme for Mesotrione Detection. IEEE SENSORS JOURNAL, v. 15, n. 4, p. 2106-2113, APR 2015. (11/17840-6, 13/09746-5, 14/12082-4, 10/04599-6, 07/05089-9, 13/21958-8, 08/57859-5)

KÁTIA R. PRIETO; LÍVIA S. DE MEDEIROS; MARSELE M. ISIDORO; LEONARDO TOFFANO; MARIA FÁTIMA G. F. DA SILVA; JOÃO B. FERNANDES; PAULO C. VIEIRA; MOACIR R. FORIM; EDSON RODRIGUES-FILHO; RODRIGO M. STUART; et al. Rapid Detection of ACTG- and AK-Toxins in Alternaria alternata by LC-ESI-MS/MS Analysis and Antifungal Properties of Citrus Compounds. Journal of the Brazilian Chemical Society, v. 27, n. 8, p. 1493-1505, 2016-08-00. (08/57859-5, 12/25299-6)

ANDRADE, MOACIR DOS SANTOS; RIBEIRO, LEANDRO DO PRADO; BORGONI, PAULO CESAR; FERNANDES DA SILVA, MARIA FATIMA DAS GRACAS; FORIM, MOACIR ROSSI; FERNANDES, JOAO BATISTA; VIEIRA, PAULO CEZAR; VENDRAMIN, JOSE DJAIR; MACHADO, MARCOS ANTONIO. Essential Oil Variation from Twenty Two Genotypes of Citrus in Brazil-Chemometric Approach and Repellency Against Diaphorina citri Kuwayama. Molecules, v. 21, n. 6, JUN 2016. (12/25299-6, 08/57859-5)

SEVERINO, VANESSA G. P.; DE FREITAS, SAMYA D. L.; BRAGA, PATRICIA A. C.; FORIM, MOACIR ROSSI; DA SILVA, MARIA FATIMA DAS G. F.; FERNANDES, JOAO B.; VIEIRA, PAULO C.; VENANCIO, TIAGO. New Limonoids from Hortia oreadica and Unexpected Coumarin from H. superba Using Chromatography over Cleaning Sephadex with Sodium Hypochlorite. Molecules, v. 19, n. 8, p. 12031-12047, AUG 2014. (08/57859-5)

SOARES, MAMBA SANTOS; DA SILVA, DANIELLE FERNANDES; FORIM, MOACIR ROSSI; DAS GRACAS FERNANDES DA SILVA, MARIA FATIMA; FERNANDES, JOAO BATISTA; VIEIRA, PAULO CEZAR; SILVA, DENISE BRENTAN; LOPES, NORBERTO PEPORINE; DE CARVALHO, SERGIO ALVES; DE SOUZA, ALESSANDRA ALVES; et al. Quantification and localization of hesperidin and rutin in Citrus sinensis grafted on C-limonia after Xylella fastidiosa infection by HPLC-UV and MALDI imaging mass spectrometry. Phytochemistry, v. 115, p. 161-170, JUL 2015. (08/57859-5)

ADALBERTO, PAULO ROBERTO; DOS SANTOS, FRANCISCO JOSE; GOLFETO, CAMILLA CALEMI; COSTA IEMMA, MONICA ROSAS; FERREIRA DE SOUZA, DULCE HELENA; CASS, QUEZIA BEZERRA. Immobilization of pectinase from Leucoagaricus gongylophorus on magnetic particles. ANALYST, v. 137, n. 20, p. 4855-4859, 2012. (08/57859-5)

OLIVEIRA, REGINA M. M.; DE SOUZA DANIEL, JULIANA F.; DE AGUIAR, INARA; DAS GRACAS FERNANDES DA SILVA, MARIA FATIMA; FERNANDES, JOAO BATISTA; CARLOS, ROSE M.. Structural effects on the hesperidin properties obtained by chelation to magnesium complexes. Journal of Inorganic Biochemistry, v. 129, p. 35-42, DEC 2013. (09/08218-0, 08/57859-5)

AMARANTE, ADRIANO M.; OLIVEIRA, GUEDMILLER S.; BUENO, CAROLINA C.; CUNHA, RICHARD A.; IERICH, JESSICA C. M.; FREITAS, LUIZ C. G.; FRANCA, EDUARDO F.; OLIVEIRA, JR., OSVALDO N.; LEITE, FABIO L.. Modeling the coverage of an AFM tip by enzymes and its application in nanobiosensors. JOURNAL OF MOLECULAR GRAPHICS & MODELLING, v. 53, p. 100-104, SEP 2014. (13/09746-5, 10/04599-6, 07/05089-9, 08/57859-5)

OLIVEIRA, GUEDMILLER S.; LEITE, FABIO L.; AMARANTE, ADRIANO M.; FRANCA, EDUARDO F.; CUNHA, RICHARD A.; BRIGGS, JAMES M.; FREITAS, LUIZ C. G.. Molecular modeling of enzyme attachment on AFM probes. JOURNAL OF MOLECULAR GRAPHICS & MODELLING, v. 45, p. 128-136, SEP 2013. (10/04599-6, 07/05089-9, 08/57859-5)

IERICH, JESSICA C. M.; OLIVEIRA, GUEDMILLER S.; VIG, ANA C. A.; AMARANTE, ADRIANO M.; FRANCA, EDUARDO F.; LEITE, FABIO L.; MASCARENHAS, YVONNE P.. A Computational Protein Structure Refinement of the Yeast Acetohydroxyacid Synthase. Journal of the Brazilian Chemical Society, v. 26, n. 8, p. 1702-1709, AUG 2015. (13/09746-5, 14/12082-4, 10/04599-6, 07/05089-9, 13/21958-8, 14/26369-3, 14/12466-7, 08/57859-5)

OLÍVIA MOREIRA SAMPAIO; MARIA FÁTIMA DAS GRAÇAS FERNANDES DA SILVA; THIAGO ANDRÉ MOURA VEIGA; BEATRIZ KING-DÍAZ; BLAS LOTINA-HENNSEN. Avaliação de furanocumarinas como inibidores da fotossíntese através de ensaios de fluorescência da clorofila a. Química Nova, v. 35, n. 11, p. 2115-2118, 2012-00-00. (08/57859-5)

MARSELE MACHADO ISIDORO; MARIA FÁTIMA DAS GRAÇAS FERNANDES DA SILVA; JOÃO BATISTA FERNANDES; PAULO CEZAR VIEIRA; ALBERTO C. ARRUDA; SEBASTIÃO DA CRUZ SILVA. Fitoquímica e quimiossistemática de Euxylophora paraensis (Rutaceae). Química Nova, v. 35, n. 11, p. 2119-2124, 2012-00-00. (08/57859-5)

BARBARA SAYURI BELLETE; ISRAEL CÍVICO GIL DE SÁ; JAIR MAFEZOLI; CRISTOVAM DO NASCIMENTO CERQUEIRA; MARIA FÁTIMA DAS GRAÇAS FERNANDES DA SILVA; JOÃO BATISTA FERNANDES; PAULO CEZAR VIEIRA; JULIO ZUKERMAN-SCHPECTOR; JOSÉ RUBENS PIRANI. Fitoquímica e quimiossistemática de Conchocarpus marginatus e C. inopinatus (Rutaceae). Química Nova, v. 35, n. 11, p. 2132-2138, 2012-00-00. (08/57859-5)

CRISTOVAM DO NASCIMENTO CERQUEIRA; DJALMA A. P. DOS SANTOS; KARLA DA SILVA MALAQUIAS; MURILO MARINHO DE CASTRO LIMA; MARIA FÁTIMA DAS GRAÇAS FERNANDES DA SILVA; JOÃO BATISTA FERNANDES; PAULO CEZAR VIEIRA. Novas N-benzoiltiraminas de Swinglea glutinosa (Rutaceae). Química Nova, v. 35, n. 11, p. 2181-2185, 2012-00-00. (08/57859-5)

NICULAU, EDENILSON DOS SANTOS; RIBEIRO, LEANDRO DO PRADO; ANSANTE, THIAGO FELIPE; FERNANDES, JOAO BATISTA; FORIM, MOACIR ROSSI; VIEIRA, PAULO CEZAR; VENDRAMIM, JOSE DJAIR; DAS GRACAS FERNANDES DA SILVA, MARIA FATIMA. Isolation of Chavibetol and Methyleugenol from Essential Oil of Pimenta pseudocaryophyllus by High Performance Liquid Chromatography. Molecules, v. 23, n. 11, NOV 2018. (08/57859-5, 11/22975-8)

NICULAU, EDENILSON DOS SANTOS; FERREIRA, DOUGLAS; RODRIGUES-FILHO, EDSON; BEHLAU, FRANKLIN; MAGNANI, RODRIGO FACCHINI; TOFFANO, LEONARDO; PRIETO, EVANDRO LUIS; FERNANDES, JOAO BATISTA; DA SILVA, MARIA FATIMA DAS GRACAS FERNANDES. MALDI-TOF Mass Spectrometry for the Diagnosis of Citrus Canker Caused by Xanthomonas citri subsp. citri. Molecules, v. 27, n. 24, p. 14-pg., 2022-12-01. (08/57859-5, 11/22975-8)

OLIVEIRA, REGINA M. M.; DE SOUZA DANIEL, JULIANA F.; CARLOS, ROSE M.. Synthesis, spectroscopic characterization and biological activity of cis-[Ru(hesperidin)(1,10 '-phenanthroline)(2)](PF6) complex. Journal of Molecular Structure, v. 1031, p. 6-pg., 2013-01-16. (09/08218-0, 08/57859-5)

Filed patent(s) as a result of this research project