Study on the wild cycle of Vaccinia virus in the municipalities of Torre de Pedra Bofete and Anhembi - São Paulo: assess the potential of rodents as reservoirs in areas with and without reports of an outbreak in cattle and humans

• Grant number: 10/07908-0
• Support Opportunities: Regular Research Grants
• Start date: July 01, 2010
• End date: December 31, 2012
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
• Principal Investigator: Jane Megid
• Grantee: Jane Megid
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
• Associated researchers: Marina Gea Peres Serafim
• Associated scholarship(s): 11/01648-9 - Study on the wild cycle of vaccinia virus in the municipalities of Torre de Pedra Bofete and Anhembi - São Paulo: Assess the potential of rodents as reservoirs in areas with and without reports of an outbreak in cattle and humans, BP.TT

Abstract

The processes of emergence of new diseases or re-emergence, especially of zoonotic origin, are mostly related to wildlife. Considering these facts, the cowpox, infection caused by vaccinia virus (VACV), presents as an important reemerging disease in Brazil, affecting herds of cattle and humans. Since the end of the world program of mass vaccination in 1980, where the World Health Organization (WHO) announced the eradication of smallpox virus, VACV outbreaks in cattle and humans has been reported and described in several regions of Brazil . There is little information on the natural host of VACV, however in 1963, VACV was isolated in a rodent of the genus Oryzomys, comprising 36 species of terrestrial habits, which may eventually have access to peridomestic areas. Currently in Brazil, several species of primates, rodents, carnivores and marsupials are sighted in areas adjacent to farms, including those already affected by VACV, however there is a lack of studies on the prevalence of OPV in Brazilian species of wild mammals, and their actual impacts to endangered populations. Thus this research project seeks to analyze the potential of wild rodents as reservoir of VACV as well as factors related to human, animal and environmental health. (AU)