Research Grants 08/10813-0 - Dirofilaria immitis, Ivermectina - BV FAPESP
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Occurence of dog filarial worms and sazonal prevalence of Dirofilaria immitis (Leidy, 1856), in their vectors in the Porto Velho municipality, Rondônia, Brasil

Grant number: 08/10813-0
Support Opportunities:Regular Research Grants
Start date: July 01, 2009
End date: June 30, 2011
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
Principal Investigator:Luís Marcelo Aranha Camargo
Grantee:Luís Marcelo Aranha Camargo
Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The canine filariose is a parasitic disease with world distribution whose the ethiological agents are nematode filarial worms. In your adult phase, the worms produce microfilarial worms through sexual reproduction. Your transmission happens through mosquitos that act as intermediate hosts. The species D. immitis is the more studied due to your cosmopolitan distribution and for eventually to sponge the man. Several methods of diagnosis of canine filariose exist, the more used are the thick blood film and the Knott method. The Ivermectin, in the dose of 6 mcg/kg, is the more used drug in the treatment and prophylaxis. The canine worm possess heteroxen cycle. The intermediate hosts are haematofagus Diptera of more than 70 species, although a dozen can just act indeed as vector. Brazil, mainly the Amazon area, possesses all the necessary characteristics to happen the transmission of canine filarioses. Besides the climate to favor the biological development of the vectors, the deforestation and the lack of basic sanitation contributes to the maintenance of a high population of vectors in the urban way. For the prevalence measure, the collections of blood will be made in the homes and in dogs submitted to exams or surgical procedures in veterinary clinics of the Bairro Nacional, Cai N'água, Baixa União da Candelária of the city of Porto Velho. The prevalence will be verified through the blood exam searching for microfilaria and for the presence of circulating antigens. It will be made collection of 2-3ml of blood of the cephalic vein with the aid of a syringe. The prevalence will be calculated by the number of positive individuals x 100 divided by the total number of examined individuals. For calculation of natural infection mosquitos will be collected, in the intra and peri-home, for xenomonitoring through suction apparel and for traps CDC. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
OGAWA, GUILHERME MAERSCHNER; DA CRUZ, EDSON NEVES; ARAUJO CUNHA, PRISCILA NAYARA; ARANHA CAMARGO, LUIS MARCELO. Canine heartworm disease in Porto Velho: first record, distribution map and occurrence of positive mosquitoes. Revista Brasileira de Parasitologia Veterinária, v. 22, n. 4, p. 559-564, . (08/10813-0)
OGAWA, GUILHERME MAERSCHNER; DA CRUZ, EDSON NEVES; ARAUJO CUNHA, PRISCILA NAYARA; ARANHA CAMARGO, LUIS MARCELO. Canine heartworm disease in Porto Velho: first record, distribution map and occurrence of positive mosquitoes. REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA, v. 22, n. 4, p. 6-pg., . (08/10813-0)