Quantitative-molecular genetic analysis for production traits, fatty acid profile and milk quality

• Grant number: 10/12929-6
• Support Opportunities: Regular Research Grants
• Start date: December 01, 2010
• End date: May 31, 2013
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Genetics and Improvement of Domestic Animals
• Principal Investigator: Gerson Barreto Mourão
• Grantee: Gerson Barreto Mourão
• Host Institution: Escola Superior de Agricultura Luiz de Queiroz (ESALQ). Universidade de São Paulo (USP). Piracicaba , SP, Brazil
• Associated researchers: Luiz Lehmann Coutinho ; Paulo Fernando Machado

Abstract

In search of increasing productivity and product quality, the animal breeding is able to identify animals with superior genetic values and adapted to the Brazilian conditions. With the contribution from the import of genetic material for use in the Brazilian dairy herds and the fact that the genetic gain for these traits has small magnitude, there is a perceived need for genetic evaluation of these animals under the national conditions of environment. Concomitantly, the milk yield with good quality traits such as the possible reduction in somatic cell count and increased contents of protein, fat and beneficial fatty acids are important objectives in dairy cattle breeding program. In this context, to maximize the potential genetic gains we can combine to the genetic evaluation the use of molecular markers as a tool to improve the selection and being the fatty acid profile an important component on human health, the purpose of this study represents an important research to livestock milk, allowing the genetic manipulation of these traits to raise the nutritional quality of milk. With the main objective of estimate genetic parameters related to production yield and milk quality, such as somatic cell counts and fatty acid profile, as well as the association of the polymorphisms of the SCD1, DGAT1, CXCR1 and TLR4 genes with these traits, besides to determine the correlation between the milk fat composition and the other components of this product. There will be monthly sampled about 2000 dairy cows in lactation and will be determinated the levels of fat, protein and the fatty acids butyric, lauric, myristic, palmitic, stearic, oleic, and conjugated linoleic besides production, somatic cell count and other milk components. The genetic-statistical model used will include the fixed effects of herd, calving season, year, class of days in milk, class of lactation and the random effect of animal besides the residual effect. For the polymorphisms study, there will be extracted DNA from the somatic cells present in milk samples and will be performed the genotyping of animals, in this case, the analysis will be added to the model the fixed effects of genotype of these genes. (AU)

Scientific publications

(11)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CARRARA, EULA REGINA; PETRINI, JULIANA; SALVIAN, MAYARA; DE OLIVEIRA, HINAYAH ROJAS; ROVADOSCKI, GREGORI ALBERTO; IUNG, LAIZA HELENA DE SOUZA; MIQUILINI, MARINA; MACHADO, PAULO FERNANDO; MOURAO, GERSON BARRETO. Genetic parameters for milk yield and quality traits of Brazilian Holstein cows as a function of temperature and humidity index. JOURNAL OF ANIMAL BREEDING AND GENETICS, v. 138, n. 6, JUN 2021. (12/15948-7, 12/24788-3, 10/12929-6, 16/15066-5)

PETRINI, JULIANA; DE SOUZA IUNG, LAIZA HELENA; PETERSEN RODRIGUEZ, MARY ANA; SALVIAN, MAYARA; ROVADOSCKI, GREGORI ALBERTO; ROBLES COLONIA, SADITT ROCIO; CASSOLI, LAERTE DAGHER; COUTINHO, LUIZ LEHMANN; MACHADO, PAULO FERNANDO; WIGGANS, GEORGE; et al. Assessing the accuracy of prediction for milk fatty acids by using a small reference population of tropical Holstein cows. JOURNAL OF ANIMAL BREEDING AND GENETICS, v. 136, n. 6, p. 453-463, NOV 2019. (12/15948-7, 10/12929-6, 12/24788-3)

CARRARA, EULA REGINA; GAYA, LEILA DE GENOVA; PETRINI, JULIANA; DE PAIVA, JOSE TEODORO; SALVIAN, MAYARA; ROVADOSCKI, GREGORI ALBERTO; MACHADO, PAULO FERNANDO; MOURAO, GERSON BARRETO. Genetic and phenotypic trends for milk fatty acids in a Holstein cattle population reared under tropical conditions. LIVESTOCK SCIENCE, v. 228, p. 84-92, OCT 2019. (12/15948-7, 16/15066-5, 10/12929-6, 12/24788-3)

SALVIAN, MAYARA; SILVEIRA, ROBSON MATEUS FREITAS; PETRINI, JULINA; ROVADOSCKI, GREGORI ALBERTO; IUNG, LAIZA HELENA DE SOUZA; RAMIREZ-DIAZ, JOHANNA; CARRARA, EULA REGINA; PERTILE, SIMONE FERNANDA NEDEL; CASSOLI, LAERTE DAGHER; MACHADO, PAULO FERNANDO; et al. Heat stress on breeding value prediction for milk yield and composition of a Brazilian Holstein cattle population. INTERNATIONAL JOURNAL OF BIOMETEOROLOGY, v. 67, n. 2, p. 8-pg., 2022-12-29. (12/15948-7, 10/12929-6, 12/24788-3)

IUNG, L. H. S.; PETRINI, J.; RAMIREZ-DIAZ, J.; SALVIAN, M.; ROVADOSCKI, G. A.; PILONETTO, F.; DAURIA, B. D.; MACHADO, P. F.; COUTINHO, L. L.; WIGGANS, G. R.; et al. Genome-wide association study for milk production traits in a Brazilian Holstein population. JOURNAL OF DAIRY SCIENCE, v. 102, n. 6, p. 5305-5314, JUN 2019. (12/24788-3, 10/12929-6, 12/15948-7)

CARRARA, EULA REGINA; DAURIA, BRAYAN DIAS; GERVASIO, IZALLY CARVALHO; SILVEIRA, ROBSON MATEUS FREITAS; ROVADOSKI, GREGORI ALBERTO; PETRINI, JULIANA; SALVIAN, MAYARA; MACHADO, PAULO FERNANDO; MOURAO, GERSON BARRETO. Comparison of Marker Effects and Breeding Values at Two Levels at THI for Milk Yield and Quality Traits in Brazilian Holstein Cows. GENES, v. 14, n. 1, p. 11-pg., 2023-01-01. (12/15948-7, 10/12929-6, 16/15066-5, 12/24788-3)

CARRARA, EULA REGINA; GAYA, LEILA DE GENOVA; DE PAIVA, JOSE TEODORO; PETRINI, JULIANA; SALVIAN, MAYARA; ROVADOSCKI, GREGORI ALBERTO; REIS, ARICIA CHAVES ZANETTI; MACHADO, PAULO FERNANDO; MOURAO, GERSON BARRETO. Impact of inbreeding on milk fatty acids of a Brazilian Holstein cattle. ANIMAL PRODUCTION SCIENCE, v. 60, n. 12, APR 2020. (16/15066-5, 12/15948-7, 12/24788-3, 10/12929-6)

DAURIA, B. D.; SIGDEL, A.; PETRINI, J.; BOSCOLLO, P. P.; PILONETTO, F.; SALVIAN, M.; REZENDE, F. M.; PEDROSA, V. B.; BITTAR, C. M. M.; MACHADO, P. F.; et al. Genetic effects of heat stress on milk fatty acids in Brazilian Holstein cattle. JOURNAL OF DAIRY SCIENCE, v. 105, n. 4, p. 10-pg., 2022-03-16. (10/12929-6)

PETRINI, JULIANA; SALGADO, RICARDO MENEZES; PETERSEN RODRIGUEZ, MARY ANA; MACHADO, PAULO FERNANDO; MOURAO, GERSON BARRETO. Machine learning methods for the prediction of milk fatty acid content. INTERNATIONAL JOURNAL OF DAIRY TECHNOLOGY, v. N/A, p. 10-pg., 2022-06-01. (10/12929-6, 12/15948-7)

PETRINI, JULIANA; DE SOUZA IUNG, LAIZA HELENA; PETERSEN RODRIGUEZ, MARY ANA; SALVIAN, MAYARA; ROVADOSCKI, GREGORI ALBERTO; ROBLES COLONIA, SADITT ROCIO; CASSOLI, LAERTE DAGHER; COUTINHO, LUIZ LEHMANN; MACHADO, PAULO FERNANDO; WIGGANS, GEORGE; et al. Assessing the accuracy of prediction for milk fatty acids by using a small reference population of tropical Holstein cows. JOURNAL OF ANIMAL BREEDING AND GENETICS, AUG 2019. (12/15948-7, 10/12929-6, 12/24788-3)

PETRINI, J.; IUNG, L. H. S.; RODRIGUEZ, M. A. P.; SALVIAN, M.; PERTILLE, F.; ROVADOSCKI, G. A.; CASSOLI, L. D.; COUTINHO, L. L.; MACHADO, P. F.; WIGGANS, G. R.; et al. Genetic parameters for milk fatty acids, milk yield and quality traits of a Holstein cattle population reared under tropical conditions. JOURNAL OF ANIMAL BREEDING AND GENETICS, v. 133, n. 5, p. 384-395, OCT 2016. (10/12929-6, 12/15948-7)