Effects of sleep deprivation upon muscle recovery

• Grant number: 10/07005-0
• Support Opportunities: Regular Research Grants
• Start date: August 01, 2011
• End date: January 31, 2014
• Field of knowledge: Biological Sciences - Biochemistry - Metabolism and Bioenergetics
• Principal Investigator: Marco Túlio de Mello
• Grantee: Marco Túlio de Mello
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil
• Associated researchers: Alessandra Medeiros ; Hanna Karen Moreira Antunes

Abstract

Sleep is known to be one of the most restorative in musculoskeletal, energy balance and endocrine function. Our aim is evaluate the effects of sleep deprivation on muscle recovery after eccentric exercise session performed in a isokinetic dynamometer. The sample will be composed of 15 men who were sedentary, clinically healthy, aged between 21 and 30 years old. For the study development, will be structured 6 experimental conditions: EXE-SLEEP condition in which the volunteers will carry out the exercise protocol and will not be subjected to any kind of sleep deprivation; Condition EXE-TOTAL, that volunteers will carry out the exercise protocol and will be sleep deprived for 60 hours followed by an overnight rebound. The volunteers will stay the entire period of each condition in the lab facility accompanied by a researcher, to prevent naps during the day and for blood samples for analysis of muscle damage markers, hormones, and pro and anti-inflammatory cytokines. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DATTILO, MURILO; MOREIRA ANTUNES, HANNA KAREN; NUNES GALBES, NADINE MARQUES; MONICO-NETO, MARCOS; SOUZA, HELTON DE SA; LUCIO DOS SANTOS QUARESMA, MARCUS VINICIUS; LEE, KIL SUN; UGRINOWITSCH, CARLOS; TUFIK, SERGIO; DE MELLO, MARCO TULIO. Effects of Sleep Deprivation on Acute Skeletal Muscle Recovery after Exercise. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, v. 52, n. 2, p. 507-514, FEB 2020. (98/14303-3, 10/07005-0)