Basis of Arterial Hypertension and Renal Dysfunctions Associated with Autosomal Dominant Polycystic Kidney Disease: Study in Distinct Models of Pkd1 Gene Deficiency in Mice

• Grant number: 10/17424-0
• Support Opportunities: Regular Research Grants
• Start date: January 01, 2011
• End date: December 31, 2012
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Luiz Fernando Onuchic
• Grantee: Luiz Fernando Onuchic
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FONSECA, JONATHAN M.; BASTOS, ANA P.; AMARAL, ANDRESSA G.; SOUSA, MAURI F.; SOUZA, LEANDRO E.; MALHEIROS, DENISE M.; PIONTEK, KLAUS; IRIGOYEN, MARIA C.; WATNICK, TERRY J.; ONUCHIC, LUIZ F.. Renal cyst growth is the main determinant for hypertension and concentrating deficit in Pkd1-deficient mice. Kidney International, v. 85, n. 5, p. 1137-1150, MAY 2014. (09/10748-7, 10/17424-0)

BALBO, BRUNO E.; AMARAL, ANDRESSA G.; FONSECA, JONATHAN M.; DE CASTRO, ISAC; SALEMI, VERA M.; SOUZA, LEANDRO E.; DOS SANTOS, FERNANDO; IRIGOYEN, MARIA C.; QIAN, FENG; CHAMMAS, ROGER; et al. Cardiac dysfunction in Pkd1-deficient mice with phenotype rescue by galectin-3 knockout. Kidney International, v. 90, n. 3, p. 580-597, SEP 2016. (10/17424-0)

NOGUEIRA FERRAZ, RENATO RIBEIRO; FONSECA, JONATHAN MACKOWIAK; GERMINO, GREGORY GEORGE; ONUCHIC, LUIZ FERNANDO; HEILBERG, ITA PFEFERMAN. Determination of urinary lithogenic parameters in murine models orthologous to autosomal dominant polycystic kidney disease. UROLITHIASIS, v. 42, n. 4, p. 301-307, AUG 2014. (10/17424-0)